Since Ly-6C is a surface marker on cDC2 that induce Th17 differentiation (Fig.3d), we evaluated cell surface Ly-6C by labeling the cells prior to lysis with an oligonucleotide-labeled Ab directed at that protein (indexed scRNA-Seq)45. Integration of sequence data corresponding to this bar-co...
Cancer Cell 6, 409–421 (2004). Article CAS PubMed Google Scholar Suzuki, E., Kapoor, V., Jassar, A. S., Kaiser, L. R. & Albelda, S. M. Gemcitabine selectively eliminates splenic GR-1+/CD11b+ myeloid suppressor cells in tumor-bearing animals and enhances antitumor immune activity....
其他名称:Antigen CD11b p170; CD11 antigen like family member B; CD11b antigen; CD49d; Cell surface glycoprotein MAC 1 alpha subunit; Cell Surface Glycoprotein MAC1 Alpha Subunit; Complement Component Receptor 3 Alpha; CR 3 alpha chain; CR3 Alpha Chain; CR3A; Integrin Alpha M; integrin ...
Through interactions with its ligands, Mac-1 participates in adhesive cell interactions. The epitope recognized by this mAb localizes to the I domain on the alpha chain of Mac-1 very close to the ligand binding site in a region that is widely exposed. CBRM1/5 blocks Mac-1 dependent ...
Conclusion: Change in cell surface expression of CD64 on peripheral blood neutrophils may be considered as a sensitive marker for detection of neonatal sepsis if used in combination with other laboratory parameters.doi:10.1016/S1885-5857(06)60130-8Minoo Adib...
CD11b/MAC-1(MicroglialMarker)Antibody- WithoutBSAandAzide-Additional Information GeneID3684 OtherNames Integrinalpha-M,CD11antigen-likefamily memberB,CR-3alphachain,Cellsurface glycoproteinMAC-1subunitalpha,Leukocyte adhesionreceptorMO1,Neutrophil
蛋白别名: antigen CD11b (p170); CD11 antigen-like family member B; CD11b; Cell surface glycoprotein MAC-1 subunit alpha; complement component 3 receptor 3 subunit; CR-3 alpha chain; Integrin alpha-M; integrin, alpha M (complement component 3 receptor 3 subunit); Leukocyte adhesion r...
and Factor X -these adhesions are critical for cell-cell and cell-matrix interactions. CD11b is expressed on 8% of spleen cells, 44% of bone marrow cells, and less than 1% of thymocytes, and is commonly used as a microglial marker in nervous tissue. The expression of CD11b increases dur...
蛋白别名:antigen CD11b (p170); CD11 antigen-like family member B; CD11b; Cell surface glycoprotein MAC-1 subunit alpha; complement component 3 receptor 3 subunit; CR-3 alpha chain; Integrin alpha-M; integrin, alpha M (complement component 3 receptor 3 subunit); Leukocyte adhesion ...
Here, we report that small hairpin RNA (shRNA) mediated LSD1 inhibition causes a remarkable transcriptional activation of myeloid lineage marker genes (CD11b/ITGAM and CD86), reduction of cell proliferation and decrease of clonogenic ability of human AML cells. Cell surface expression of CD11b ...