单核细胞衍生的巨噬细胞继续细分的话,包括: 血管周围巨噬细胞(CD11b+CD45hiF4/80+CD163+CD206+) 脑膜巨噬细胞(CD11b+CD45hiF4/80+CD163-CD206+) 脉络从巨噬细胞(CD11b+CD45hiCD163-MHCIIhi) 6. 小鼠脾脏组织 巨噬...
图11显示了流式细胞术分析的圈门策略。 图11A显示了流式细胞术分析结果,图中CD45+F4/80hiSiglec-F-定义为脂肪组织巨噬细胞,CD45+F4/80+Siglec-F+为嗜酸性粒细胞,CD45+NK1.1+为自然杀伤细胞,CD45+Ly6G+为中性粒细胞。 图11B显示了脂肪组织的淋巴细胞流式细胞术分析结果,图中包括CD19+B细胞、CD3+CD8+T细...
Bennett JL, Elhofy A, Canto MC, Tani M, Ransohoff RM, Karpus WJ: CCL2 transgene expression in the central nervous system directs diffuse infiltration of CD45 high CD11b + monocytes and enhanced Theiler's murine encephalomyelitis virus-induced demyelinating disease. J Neurovirol 2003:9:623–...
Fig. 4: Ly-6C+cDC2 are sufficient for induction of Th17-dependent neutrophilic airway inflammation. a–dAnalysis of cDCs (CD45+CD11c+I-A+CD88–F4/80–Siglec-F–Live/Dead–) in the lungs of WT C57BL/6, C57BL/6-Batf3–/–and C57BL/6-Batf3–/–∆DC mice at steady state, inclu...
Combined Inhibition of CCL2, CX3CR1, and CCR5 Abrogates Ly6Chi and Ly6Clo Monocytosis and Almost Abolishes Atherosclerosis in Hypercholesterolemic Mice Monocytes are critical mediators of atherogenesis. Deletion of individual chemokines or chemokine receptors leads to significant but only partial inhibitio...
MR Hussein,HI Hassan,ERM Hofny,... - 《Journal of Clinical Pathology》 被引量: 80发表: 2005年 Expression of survivin in lung eosinophils is associated with pathology in a mouse model of allergic asthma Humans vary markedly in their propensity to develop asthma, despite often being exposed to...
Locally organised and activated Fth1hi neutrophils aggravate inflammation of acute lung injury in an IL-10-dependent manner Article Open access 13 December 2022 Dexamethasone modulates immature neutrophils and interferon programming in severe COVID-19 Article Open access 15 November 2021 Plasma IL...
CD103+CD11b+ dendritic cells (DCs) are unique to the intestine, but the factors governing their differentiation are unclear. Here we show that transforming growth factor receptor 1 (TGFβR1) has an indispensable, cell intrinsic role in the development of
Role of beta 1 and beta 2 integrins in the adhesion of human CD34hi stem cells to bone marrow stroma. J Clin Invest, 90 (2) (1992), pp. 358-367 View in ScopusGoogle Scholar 36 MN Dworzak, A Schumich, D Printz, et al. CD20 up-regulation in pediatric B-cell precursor acute lympho...
Using the FDA-approved CellSearch platform (Figure 1B), we also detected CTC (defined as EpCAM+CK+DAPI+CD45−)–neutrophil clusters in metastatic breast cancer patients (Figure 1B). Recently, we found that ICAM-1 expression was increased by 200-fold in lung metastases, compared to primary...