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CD13/CD16成熟模式异常显示出中幼粒细胞和晚幼粒细胞增多,而CD13+CD16+中性粒细胞减少[4]。 还有一些抗原,如CD64,CD10和CD56也在MDS粒细胞上的异常表达。淋系抗原,如CD2,CD5,CD7和CD19也会在髓系前体细胞和成熟细胞上异常表达[1]。MDS患者还有一个共同异常:成熟粒细胞上表达不成熟粒细胞的抗原,如CD11b和...
CD11b (Leu15) epitope is expressed on 20-30% of peripheral blood lymphocytes, including CD16+ large granular lytnphocytes and CD8+ cells. This study confirms that 30% of CD8+ lymphocytes and virtually all CD16+ NK cells from healthy subjects express this determinant. In parallel, our data...
We performed FCM using 5 granulocyte/monocyte panels (CD15/CD10/CD45, CD64/CD33/CD45, CD16/CD13/CD45, CD16/CD11b/CD45, and CD56/CD19/CD7/CD45) to examine the positive rate in MDS and controls, and to find an optimal combination that maximizes the detection rate of MDS. In MDS...
M5b具有重要鉴别意义.其中单核细胞比例增高,伴有CD2,CD56异常表达,CD14拖尾现象,CD15缺失或减低及成熟粒细胞CD13-CD11b-CD16表达规律异常,对CMML诊断具有重要意义... 王韫秀,张继红,胡延平,... - 《中国实验血液学杂志》 被引量: 23发表: 2012年 CD56+急性单核细胞白血病的临床特征及预后分析 本研究探讨CD56...
Looking for online definition of CD11b in the Medical Dictionary? CD11b explanation free. What is CD11b? Meaning of CD11b medical term. What does CD11b mean?
transplanted LDL-R−/−mice expressed CD11b. After consuming a high-fat diet for 16 weeks the mean lesionaortic valvearea, cholesterol accumulation in the aorta, and the degree of intimal macrophage infiltration were similar in mice reconstituted with either CD11b+/+or CD11b−/−bone ...
在另一优选例中,所述的抑制剂抑制CD11b与SFK的相互作用。 在另一优选例中,所述的抑制剂抑制CD11b与整合素β2(CD18)的结合。 在另一优选例中,所述的制剂或组合物还用于抑制SHP-1的活性和/或表达。 在另一优选例中,所述的制剂或组合物还用于抑制SFK的活性和/或表达。
Under selective inflammatory conditions, CD11b expression is upregulated and differential CD11bpos AMΦ proportions can distinguish between the peak and resolution of acute lung inflammation, respectively.15 This scenario (either an absence or presence of inflammation-associated CD11bpos AMΦs) is ...
were limited by the sialic acid-SIGLEC-5/14 interaction. During neutrophil-tumor cell conjugate formation, we found that inhibition of the interaction between tumor-expressed sialic acids and SIGLEC-5/14 on neutrophils increased the CD11b/CD18 high affinity conformation. By dynamic acoustic force me...