11. 脂肪组织 小鼠脂肪组织巨噬细胞同样可以用CD11b+、F4/80+作为标志物,但是F4/80mid群包含嗜酸性粒细胞 (Siglec-F+) 和中性粒细胞(GR1+),因此,圈门的时候要十分小心,只要圈下图中1门的位置,进一步可以通过CD11c+和CD301+/...
刺激24小时后,用流式的方法检测极化后M1、M2标志蛋白的表达。M1巨噬细胞上调表达CD86、MHCⅡ、CD11c等,M2巨噬细胞上调表达CD206等; 实验结果举例: 参考文献: 1. JoVE. June 2013 |https://doi.org/10.3791/50323 2. Sci Rep. 2020 |https://doi.org/10.1038/s41598-020-57677-5 THP-1细胞向M1,M2的极...
Background: We investigated the potential role of several pattern-recognition receptors (PRRs; CD11b, CD11c, CD32, CD206, CD209, and dectin-1) in adult-onset Still's disease (AOSD). Methods: The study included 13 untreated AOSD patients, 19 rheumatoid arthritis (RA) patients (as a ...
Google Share on Facebook CD11b a type I transmembrane protein found on monocytes, macrophages, granulocytes, some B cells, dendritic cells, and natural killer cells that facilitates cell adhesion, phagocytosis, and/or chemotaxis; expressed in some B-cell chronic lymphocytic leukemias, most acute non...
To further characterize and classify them, we generated genome-wide transcriptional profiles of sorted colon CD11chighMHCII þ cells (Figure 1a,b) isolated from control (steady state) or DSS-treated mice (day 4). A hierarchical clustering of the differentially expressed genes using Pearson's ...
Antigen CD11b (p170); CD11 antigen like family member B; CD11 antigen like family member C; CD11B; CD11C; CellAnti-CD11b抗体 surface glycoprotein MAC 1 subunit alpha; CR 3 alpha chain; CR3A; Integrin alpha M; Integrin alpha X; Integrin, alpha M (complement component 3 receptor 3 subu...
Overlay of BAL cell (blue) and blood neutrophil (red) staining with anti-CD11b and anti-CD11c Abs shows distinct inflammatory BAL profiles in individual mice (n=3–6, right panel). AMΦ CD11b upregulation indicated as a rightwards shift of AMΦ CD11b expression with respect to blood ...
此研究旨在探讨几种模式识别受体(PRRs,CD11b,CD11c,CD32, CD206,CD209和dectin-1)在成人发病Still病(AOSD)中的潜在作用。 摘要-方法 该研究包括13名未治疗的AOSD患者,19名类风湿性关节炎(RA)患者(作为疾病控制)和19名健康对照(HC)。流式细胞术方法定量检测外周血PRR水平。采用酶联免疫吸附试验检测血清白细胞介...
(CD11c) promoter (ItgaxCrexDTAfx). In these mice, previously termed ∆DC42, manyCd11c-expressing cells, including cDCs, are reported to undergo spontaneous cell death. Our experiments confirmed this, although some cDC1 and Ly-6C+cDC2 remained (Supplementary Fig.8a–d). To selectively reduce ...