11. 脂肪组织 小鼠脂肪组织巨噬细胞同样可以用CD11b+、F4/80+作为标志物,但是F4/80mid群包含嗜酸性粒细胞 (Siglec-F+) 和中性粒细胞(GR1+),因此,圈门的时候要十分小心,只要圈下图中1门的位置,进一步可以通过CD11c+和CD301+/C...
Both populations of Gr1+CD11b+ cells expressed high levels of arginase-1, and IL-17, additional markers of myeloid derived suppressor cells. We then sorted the Gr1hi and Gr1int populations from M. tuberculosis infected NOS-/- mice and placed the sorted both Gr1int populations at different ...
髓源性抑制细胞(MDSC)作为异质性的Gr1+CD11b+的未成熟细胞群, 与具有免疫抑制特性的程序性细胞死亡受体-1(PD-1)及其配体(PD-L1)在脓毒症晚期免疫过程中发挥... 许亦菲,臧学峰,陈炜 - 《中华危重病急救医学》 被引量: 0发表: 2024年 整合素CD11b在病毒感染中的作用研究进展 整合素CD11b是重要的黏附分子和...
Gr1(+)CD11b(+) cells expressed high levels of arginase-1, and IL-17, additional markers of myeloid derived suppressor cells. We then sorted the Gr1(hi) and Gr1(int) populations from M. tuberculosis infected NOS-/- mice and placed the sorted both Gr1(int) populations at different ratios ...
Both populations of Gr1(+)CD11b(+) cells expressed high levels of arginase-1, and IL-17, additional markers of myeloid derived suppressor cells. We then sorted the Gr1(hi) and Gr1(int) populations from M. tuberculosis infected NOS-/- mice and placed the sorted both Gr1(int) populations ...
Gr1+ Inflammatory Monocytes Are Required for Mucosal Resistance to the Pathogen Toxoplasma gondii 2008, Immunity Show abstract Toxoplasmosis - A global threat. Correlation of latent toxoplasmosis with specific disease burden in a set of 88 countries 2014, PLoS ONE Listeria monocytogenes: Epidemiology, hu...
Thus, S100A9 is differentially expressed within the CD11b+Gr1+ cell compartment where the Ly6C+G+ cells is the main S100A9 expressing cell population. Figure 1 Expression of S100A9 in the splenic CD11b+cells. A. Dot-plots from FACS analysis to illustrate the gating to obtain the different ...
Interestingly, Gr1hiCD11b+, as well as Gr1lowCD11b+, cells have been characterized as granulocytic and monocytic myeloid derived suppressor cells (MDSCs), respectively. Hence, we hypothesized that - Gr1hiCD11b+ cells suppress B cell activation and differentiation and protect against lupus-like ...
Because vagal signals stabilize α7 nAChR+CD11b+ cells in the spleen via phosphorylation of AKT1, we tested whether vagotomy or double deletion of Chrna7 and Itgam could reduce p-AKT1ser473+ in splenic ly6CintGr1hi neutrophils and ly6Chi monocytes. We IT challenged sham, vagotomized and Chrna...
Interestingly, LPS not only caused the expected increase in the frequency of a CD11b + Gr1hi population, but also a second population, with the phenotype CD11b+ Gr1int also promoted by LPS (Figure 1a). The frequency of the CD11b + Gr1int population increased with each instillation of LPS...