CD117(也称c-Kit),是许多干细胞群的典型标志物,在人和小鼠HSPC表面均表达,且能被迅速内化,已有研究报道通过CD117靶向抗体药物偶联物选择性清除HSPC。1.2 传统治疗方法的局限性 传统的离体自体造血干细胞基因治疗需收集患者自身干细胞,体外培养用于基因转移或编辑,...
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KIT (c-KIT) is a proto-oncogene and a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). KIT was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. KIT together with its ligand regulates growth and ac...
KIT (c-KIT) is a proto-oncogene and a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). KIT was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. KIT together with its ligand regulates growth and activation...
View our 47 CD117/c-kit products for your research including CD117/c-kit Primary Antibodies, Small Molecules, Proteins and Enzymes, Proteome Profiler Antibody Arrays, ELISAs, cDNA Clones, and Luminex Assays.
CD117，即c-Kit，是一种细胞因子受体，广泛存在于造血干细胞和多种细胞类型表面。作为III型受体酪氨酸激酶，CD117通过结合干细胞因子形成二聚体，激活自身酪氨酸激酶活性。随后，该活性会磷酸化并激活信号转导分子，这一过程对细胞存活、增殖和分化至关重要。在造血干细胞、多能干细胞以及常见的髓系...
CD117，又名c-Kit，是一个细胞因子受体，在造血干细胞和其它细胞类型的细胞表面表达。CD117的信号转导对细胞存活、增殖、分化起作用。造血干细胞、多能干细胞和常见的髓系祖细胞可高水平表达CD117。该基因的激活突变与肥大细胞病有关，而失活突变与基因缺陷的斑驳病相关。c-kit基因位于人染色体4q12-13...
CD117/c-kit 蛋白 | MedChemExpress(MCE) 英文名称: CD117; SCFR; c-Kit; KIT 总访问: 20 国产/进口: 进口 半年访问: 9 产地/品牌: MedChemExpress(MCE) 产品类别: 生化试剂 规格: 5μg; 10 μg; 50 μg 最后更新: 2025-2-13 货号: HY-P78712 CAS 号: 参考报价: 550; 900; 2500 ...
货号: PA6946 备案号: RUO号 克隆号: YN02256m 应用: IHC-p 阳性部位: 细胞膜/质 修复方式: EDTA热修复 产品描述: CD117是原癌基因编码的具有酪氨酸激酶生长因子受体蛋白,为胃肠间质瘤免疫组化检查特异性标记物。CD117还可以用于鉴别淋巴瘤中肥大细胞发生的肿瘤,和作为部分睾丸生殖细胞瘤的标记物。胸腺鳞状...
产品概述 Abcam s c-Kit Human in vitro ELISA (Enzyme-Linked Immunosorbent Assay) kit is designed for the quantitative measurement of c-Kit in Human serum, plasma, buffered solutions or supernatants.A monoclonal antibody specific for c-Kit has been coated onto the wells of the microtiter strips ...