The observed delay in tumor growth due to PRRT is similar to the results reported by Cullinane et al., who evaluated the effect of [177Lu]Lu-DOTA-TATE in a combined regime with the PARP-inhibitor talazoparib using Balb/c nude mice with AR42J-tumors [16]. In this study, mice treated ...
the IgM isotype antibodies were recovered from BALB/c mice immunized with senescent mouse lung fibroblasts, where clone 94H was able to bind to the modified form of vimentin, which undergoes a post-translational change in cysteine 328 during senescence (C328) forming a malondialdehyde oxidative add...