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After CD276 silencing, the cell cycle of LEPCs was prone to remain at the G0/G1 phase, and the cell migration rates as well as transwell and wound‐healing migration were decreased. CD276 knockdown in LEPCs increased the G1 phase regulators cyclin D2/D3/E1‐cyclin‐dependent kinases (...
Other studies suggest that the primary role of SDC-1 is the organization of Fn at the host cell surface, through the GAG binding domains of Fn (12). Various bacteria are then able to interact directly with Fn through FnBPs located in their outer membrane (42). Our data suggest that the...