CD-RAP was originally described in chondrogenesis of the normotopic skeleton and in fracture healing [27-30], but has also been described as a small soluble protein secreted from malignant melanoma cell lines in vitro and serves as a serum marker for progression of malignant melanoma [27,31]....
44% of bone marrow cells, and less than 1% of thymocytes, and is commonly used as a microglial marker in nervous tissue. The expression of CD11b increases during monocyte maturation and expression levels vary on tissue macrophages. Further, peritoneal macrophages are reported to express higher lev...
CD72 is a pan B-cell marker covering the full range of differentiation from the very early stages of B cells to mature surface Ig+ B cells (PMID: 1384316). It is expressed in all stages of B cell development except plasma cells. CD72 is also expressed by dendritic cells, tissue ...
Being highly expressed on NKT cells, CD186 is often used as a proxy marker of this cell subset. 仅用于科研。不用于诊断过程。未经明确授权不得转售。 This is a modal window. This video is either unavailable or not supported in this browser Error Code: MEDIA_ERR_SRC_NOT_SUPPORTED...
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CD163is a monocyte/macrophage specificmembrane markercleaved from thesurfaceof activated macrophages as a soluble form (sCD1639) when inflammation of theCNSoccurs. sCD163 can be detected in blood andCSF[59]. Fabriek et al.[212]found an up-regulation of plasma sCD163 and a down-regulation of...
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form neurospheres and differentiate into various neurallineages. When transplanted into immunocompromised mice, CD15+cells were at least 100-fold more tumorigenic when compared to CD15−cells. Unlike the CD15−population, the CD15+cells were able to recapitulate the heterogeneic marker expression...
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4. Can CD206 marker be used as a marker of M2 macrophages? The activation of macrophages with various stimuli leads to their polarization into classical (M1) or alternatively activated (M2) subtypes spectrums and both subtypes differ in their regulatory and effector functions (PMID: 24669294). ...