抗体名称Anti-CCR4 Antibody 指标别名C-C motif chemokine receptor 4;CC-CKR-4;CD194;CKR4;CMKBR4;ChemR13;HGCN:14099;K5-5;CCR4 克隆性Polyclonal 检验物种human 应用范围IHC,WB 基因名称CCR4 抗体来源Rabbit 抗体类型IgG 免疫原A synthetic peptide corresponding to a sequence at the C-terminus of human ...
而来自Therapeutic antibody database数据显示，CCR4已有多款在研抗体药物处于临床前阶段，但尚未公布具体的药物临床信息。近年来，CCR4在过敏性疾病、自身免疫性疾病，尤其在肿瘤研究中越来越受到重视，因其在Treg细胞行使Treg细胞肿瘤免疫抑制调控功能中扮演重要角色，这些研究的发现，提示CCR4或可成为肿瘤免疫靶向治疗的新...
High Specificity Validated by Western Blot (WB) CSB-MP004843HU is detected by Mouse anti-6*His monoclonal antibody.Excellent Bioactivity Validated by Functional ELISA Immobilized Human CCR4 at 10 μg/ml can bind Anti-CCR4 recombinant antibody (CSB-RA004843MA01HU), the EC50 is 362.3-630.8 ng/...
Background: CCR4 CCR4 (C-C chemokine receptor 4) is a 42 kDa member of the GPCR #1 family of transmembrane proteins. In rodent, functional CCR4 is expressed on fully differentiated CD4+Th2 cells, invariant CD4+NKT cells, and neurons. It is the receptor for CCL17/TARC, CCL22/MDC and ...
ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB) 免疫原 免疫原详情,请参考产品官网页面信息 来源宿主 Rabbit 反应性 Caenorhabditis elegans 保存建议 -20 degree C for long term storage 其他 MyBioSource公司成立于2006年,总部位于美国的加利福尼亚,致力于为生命科学研究提供一站式的产品和服务。
aWestern blot showing subcellular localization of ectopically expressed MARTRE1/2 in TT2 mESCs. Cyto, cytoplasmic extracts. Nuc, nucleus extracts. One representative from two biological replicates is shown.bScatter plot showing gene-level poly(A) tail lengths in TT2 mESCs expressing doxycycline-inducibl...
compared to control thymocytes (Fig.3cand Supplementary Fig.3a). Moreover, in vivo injection of an anti-CD3 antibody decreased the number of DP thymocytes more efficiently inCnot3f/fCd4-Cremice than in control mice (Fig.3d). In contrast, the absence of CNOT3 did not appreciably influence ...
a Western blot analysis of RNF219 expression in parental HeLa, RNF219 KO cells and RNF219 KO cells stably expressing 3xFS-RNF219-WT or -RINGmut using antibodies as indicated. The relative RNF219 expression level is given below; tubulin serves as loading control. b Scatter plot and margin...
Mouse anti-V5 primary antibody (Invitrogen; catalog no.: R960-25) at 1:5000 dilution in blotto. Rabbit anti-V5 (Cell Signaling Technologies; catalog no.: 13202S) at 1:5000 dilution in TBST. Mouse anti-Tubulin (Cell Signaling Technologies; catalog no.: 3873) at 1:1000 dilution in blotto...
1k,l. (l) Western blotting analysis showing comparable expression of the MS2-HA-tagged proteins used in h–k. The asterisk indicates cross-reactivity with the anti-HA antibody. Error bars represent s.d. from three independent experiments. Full images of western and northern blottings are shown...