根据无细胞共培养上清液中的 ELISA 分析,曲妥珠单抗诱导的 NK 细胞对 SKBR3、BT474 和 HC1954 HER2 阳性乳腺癌细胞的活化会导致 CCL5、IFN-γ 的分泌以及随之而来的 CXCL9 和 CXCL10 的产生(图 2A)。包括 I 型 IFNs(抗 ...
适用范围/预期用途本试剂盒通过定量检测人体血清或血浆中IFN-γ诱导的蛋白10(IP-10,又名CXCL10)、单核细胞趋化因子(MCP-1,又名CCL2)、IFN-γ诱导的单核因子(MIG,又名CXCL9)和受激活调节正常T细胞表达和分泌因子(RANTES,又名CCL5)的表达,为医师提供诊断的辅助信息。
Synergistic induction of CCL5, CXCL9 and CXCL10 by IFN-γ and NLRs ligands on human fibroblast-like synoviocytes—A potential immunopathological mechanism for joint inflammation in rheumatoid arthritis - ScienceDirectXiaoyan Yu aZhixin Song a
In a previous study, it has been shown that EHV-1 infected PBMC can up-regulate inflammatory chemokines CCL5, CXCL9 and CXCL10, and down-regulate chemotactic CCL2 and CCL3 with clear strain differences [15]. During an infec- tion with another alphaherpesvirus, HSV-1, in mice, it has ...
CXCL9 (MIG) CXCR3 Migration of Th1, CD8 and NK cellsTh1 response - Upregulated early post SARS-CoV-2 infection - Higher levels detected in mildly symptomatic and severe cases compared to asymptomatic CXCL10 (IP-10) CXCR3 Migration of Th1, CD8 and NK cellsTh1 response - Produced by activa...
铁死亡诱导剂咪唑酮埃拉斯汀(IKE)通过抑制IL-6、CCL5及CXCL9分泌缓解CIA小鼠的肺纤维化 认领 被引量:2 Ferroptosis inducer IKE ameliorate pulmonary fibrosis in collagen-induced arthritis(CIA)mice via decreasing the expression of IL-6,CCL5 and CXCL9 ...
Single-cell RNA-sequencing (scRNA-seq) data were used to identify the hub gene-expressing cell types and their intercellular interactions. Results Through an extensive bioinformatics analysis, CXCL9, CCL5, GZMA and GZMK were identified as hub genes that distinguished IPAH patients from controls. ...
研究表明,干燥综合征(SS)患者泪腺角膜上皮细胞CXCL9、CXCL10、 CXCL11 及受体CXCR3 表达均升高;Goulvestre 等 [19] 通过对甲状腺组织中表达的细胞因子和相应 趋化因子研究,得出CCL21、CXCL12、CXCL13、CCL22 在自身免疫性甲状腺疾病(AITD)患者 的甲状腺组织中的表达增加,其中自身免疫性疾病甲状腺组织中有异位二级淋...
Single-cell RNA-sequencing (scRNA-seq) data were used to identify the hub gene-expressing cell types and their intercellular interactions. Results Through an extensive bioinformatics analysis, CXCL9, CCL5, GZMA and GZMK were identified as hub genes that distinguished IPAH patients from controls...
Our aim was to determine the serum levels of chemokines and investigate the association of chemokine gene polymorphisms with childhood HSP. Serum levels of chemokines (interleukin-8/CXCL8, MCP-1/CCL2, RANTES/CCL5, MIG/CXCL9, and IP-10/CXCL10) were determined using cytometric beads arrays. ...