Enables chemokine activity. Involved in several processes, including astrocyte cell migration; macrophage chemotaxis; and positive regulation of macromolecule metabolic process. Located in extracellular space. Is expressed in articular cartilage; cartilage; knee joint; lung; and radius. Human ortholog(s) ...
AMP-activated protein kinase activation mediates CCL3-induced cell migration and matrix metalloproteinase-2 expression in human chondrosarcomaAMPKCCL3ChondrosarcomaMMP-2CCR5Medicine(GeneralBiological Sciences(GeneralChemokine (C-C motif) ligand 3 (CCL3), also known as macrophage inflammatory protein-1??, ...
CCL9 (macrophage inflammatory peptide gamma, MIP-1), like CCL3, binds the receptor CCR1, and regulates osteoclast function [290]. Injection of M-CSF to induce osteoclastogenesis and bone resorption in osteopetrotic tl/tl rats, which lack M-CSF, caused a rapid (within 2 days) upregulation...
Description: This CR3M monoclonal antibody reacts with human CCL3. CCL3, also known as MIP-1 alpha (Macrophage Inflammatory Protein 1 alpha), is a member of the CC- subfamily of chemokines and is most closely related to CCL4, or MIP-1 beta. These proteins play critical roles in the rec...
Macrophage inflammatory protein 1-alpha (MIP-1 alpha ) triggers migration and signaling cascades mediating survival and proliferation in multiple myeloma (MM) cells. Blood. 2003; 101:3568-3573. 47. Burger JA, Quiroga MP, Hartmann E, Burkle A, Wierda WG, Keating MJ, Rosenwald A. High-level...
Description: This CR3M monoclonal antibody reacts with human CCL3. CCL3, also known as MIP-1 alpha (Macrophage Inflammatory Protein 1 alpha), is a member of the CC- subfamily of chemokines and is most closely related to CCL4, or MIP-1 beta. These proteins play critic...
CCL9 (macrophage inflammatory peptide gamma, MIP-1γ), like CCL3, binds the receptor CCR1, and regulates osteoclast function [279]. Injection of M-CSF to induce osteoclastogenesis and bone resorption in osteopetrotic tl/tl rats, which lack M-CSF, caused a rapid (within 2 days) upregulati...
Enables chemokine activity. Involved in several processes, including astrocyte cell migration; macrophage chemotaxis; and positive regulation of macromolecule metabolic process. Located in extracellular space. Is expressed in articular cartilage; cartilage; knee joint; lung; and radius. Human ortholog(s) ...
“macrophage inflammatory protein-1 alpha” (MIP-1α). Subsequently, a high nucleotide sequence similarity (69%) was found between the murine MIP-1α cDNA and a reported human cDNA cloned from stimulated lymphocytes, initially called LD78α or GOS19, assuming to be the human counterpart to ...
Description: The CCL3 polyclonal antibody reacts with both mouse and rat CCL3, also known as MIP-1α (macrophage inflammatory protein-1 alpha). The antibody was generated using E. coli-expressed amino acids 1-69 of mature rat CCL3 as an immunogen. CCL3 is a 69-amino acid CC chemokine...