研究人员认为,联合疗法可能是一个可行的解决方案,当抗CCL2治疗与抗IL-6或抗VEGF治疗相结合,结果发现转移灶明显减少,并能增加存活率。 我们的结果需要谨慎考虑anti-ccl2在转移性疾病治疗,强调肿瘤的微环境是成功的抗转移治疗的一个关键因素。
白细胞介素6目的:检测肌萎缩侧索硬化病人的外周血趋化因子配体2(chemokine ligand-2,CCL2)和白细胞介素6(interleukin 6,IL-6)的表达水平及与认知功能评分的相关性.方法:选择肌萎缩侧索硬化病人32例(观察组)和肌肉病病人(对照组)20例,ELISA法检测血浆CCL2和IL-6的水平,利用简易智能量表(Mini-mental Stat... ...
通过二代高通量RNA测序和定量PCR、ELISA等实验对两组肠炎小鼠肠道差异基因进行筛选与验证,我们发现IL6、CCL2和CSF3等细胞因子在TLR4-KO小鼠肠道中显著下调。最后我们对这些细胞因子在肠癌上皮细胞中进行了功能验证,并且构建了以TLR4分子为...
Association of IL6 and CCL2 gene polymorphisms with the outcome of allogeneic haematopoietic stem cell transplantation. Bone Marrow Transplant. 2009;44(4):227–35. : 10.1038/bmt.2009.16 .Association of IL-6 and CCL2 gene polymorphisms with the outcome of allogeneic haematopoietic...
Zhu, X. et al. Proinflammatory status in the aqueous humor of high myopic cataract eyes. Exp. Eye Res. 142, 13–18 (2016). CAS PubMed Google Scholar Yamamoto, Y. et al. Associations of inflammatory cytokines with choroidal neovascularization in highly myopic eyes. Retina 35, 344–350 (...
2008. 38: 1877–1888 DOI 10.1002/eji.200737973 Cellular immune response 1877 CCL2 recruitment of IL-6-producing CD11b+ monocytes to the draining lymph nodes during the initiation of Th17-dependent B cell-mediated autoimmunity Ying Bai*1,2,6, Ruolan Liu*2, DeRen Huang3, Antonio La Cava4,...
Conclusions: : As expected, thrombin treatment of corneal fibroblasts increased expression of proinflammatory chemokines such as CXCL1, CCL2, IL-6 and IL-8. Expression of CXCL10 and CCL13 mRNA and proteins were also increased by thrombin treatment of stromal fibroblasts. Regulation of CXCL10 and...
(英)IL-4通过Jak1、2 Stat6信号转导途径调节角质形成细胞中的趋化因子CCL26:对特应性皮炎的影响.pdf,Molecular Immunology 50 (2012) 91–97 Contents lists available at SciVerse ScienceDirect Molecular Immunology j o u r n a l h o m e p a g e : w w w. elsev /l
货号:HB-P9S982X 规格:96T 1800元/48T 1200元 用途:用于科研实验。 保存及有效期: 1.试剂盒保存: 2-8℃。 2.有效期: 6个月 特点:操作简单 规格:96T/48T 供货能力:现货,可根据客户需求批量订制生产。 公司经营的ELISA检测试剂盒种类齐全, 可以检测:人、大鼠、小鼠、豚鼠、鹿、羊、鸡、鸭、鱼、兔子、猪...
The proneural-mesenchymal (PN-MES) transformation of glioma stem cells (GSCs) can significantly increase proliferation, invasion, chemotherapy tolerance, and recurrence. M2-like polarization of tumor-associated macrophages (TAMs) has a strong immunosuppressive effect, promoting tumor malignancy and angiogenes...