Predicted to enable CCR2 chemokine receptor binding activity and chemokine activity. Involved in negative regulation of leukocyte proliferation and positive regulation of leukocyte migration. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in several diseases, inclu...
Verified Reactivity :Human Antibody Type :Monoclonal Host Species :Mouse Immunogen :Recombinant protein Formulation :Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. Preparation :The antibody was purified by affinity chromatography and conjugated with biotin under optimalconditions. ...
CCL2was the firstchemokinefound and studied in the human body and is also known as monocyte chemoattractant protein-1 (MCP-1)(Bianconi et al., 2018;Yoshimura et al., 1989). Under normal physiological conditions, CCL2 is expressed in small and medium-sized neurones of theDRGand superficial ...
(chemokine CC). MCP4 has a role in accumulation of leukocytes during inflammation. MCP4 is known to interact with HNRNPH3, CCBP2, CCR5, CCRL1 and CCR3. MCP4 has been studied in relation to asthma, rheumatoid arthritis, lateral sclerosis, allergic rhinitis and several other diseases and ...
The role of CCL13 in human disorders and existing CCL13-focused therapies are outlined in this study. The function of CCL13 in rheumatic diseases, skin conditions, and cancer is comparatively well-established, and some studies also suggest that it may be involved in ocular disorders, orthopedic...
24, and CCL26. CCL13 is involved ininflammatory diseases such as rheumatoid arthritis (RA), atherosclerosis, and asthma. Highlevels of CCL13 have been detected in the synovial fluid of patients with RA, in serum ofasthmatic patients, and in plasma of patients with symptomatic carotid ...
(chemokine CC). MCP4 has a role in accumulation of leukocytes during inflammation. MCP4 is known to interact with HNRNPH3, CCBP2, CCR5, CCRL1 and CCR3. MCP4 has been studied in relation to asthma, rheumatoid arthritis, lateral sclerosis, allergic rhinitis and several other diseases and ...
E. coli-derived recombinant human CCL13/MCP-4Gln24-Thr98Accession # Q99616.1 Specificity Detects human CCL13/MCP‑4 in ELISAs. In sandwich immunoassays, less than 1% cross-reactivity with recombinant human (rh) CCL2 is observed and no significant cross-reactivity or interference with rhCCL...
MCP4 is known to interact with HNRNPH3, CCBP2, CCR5, CCRL1 and CCR3. MCP4 has been studied in relation to asthma, rheumatoid arthritis, lateral sclerosis, allergic rhinitis and several other diseases and disorders. Alternate Names MCP-4, MCP4 Gene Symbol CCL13 Additional CCL13/MCP...
MCP4 is known to interact with HNRNPH3, CCBP2, CCR5, CCRL1 and CCR3. MCP4 has been studied in relation to asthma, rheumatoid arthritis, lateral sclerosis, allergic rhinitis and several other diseases and disorders. Alternate Names MCP-4, MCP4 Gene Symbol CCL13 Additional CCL13/MCP...