Gene expression analyses were conducted with the primer sequences provided in Supplementary Table 1. Statistics and reproducibility No statistical methods were used to predetermine sample sizes. The experiments were not randomized. A minimum number of mice was selected based on preliminary studies, with...
points; (J) Statistical analysis of relative fluorescence intensity in immunofluorescence (IF) images of CCL5-positive cells in MCF-7 and MDA-MB-231 cells - red: CCL5 labeled with AlexaFluor594, DAPI-stained cell nuclei, bar = 25 μm. Cell experiments were repeated three times, where “...
Live cells were gated first. Then M1 macrophages were gated on CD45+CD11b+F4/80+CD86+ population. M2 macrophages were gated on CD45+CD11b+F4/80+CD206+ population. Additional file 2: Table S1. Signature genes for defining stemness states and macrophage phenotypes. ...
Other clinical end points included improvement in body surface area (calculated using the patient’s palm size as a 1% equivalent), PGA score, and the target lesion site (the PGA score for a single plaque selected at baseline for each patient). Routine laboratory tests and monitoring of vital...
In another set, CCR2 antagonist pretreatment of PMφ was performed at indicated time points followed by overnight incubation with MSC-CM. (D) Cartoon shows the experimental schemes for results described in (E)–(G). Mice (n = 5 per test group) received 4.0% (w/v) of DSS orally for ...
Chart Line chart with 391 data points. The chart has 1 X axis displaying Time. Range: 2025-05-16 09:26:06 to 2025-05-16 16:03:54. The chart has 1 Y axis displaying values. Range: 76 to 80. 10 am11 am12 pm1 pm2 pm3 pm4 pm$76$77$78$79$80 End of interactive chart. Peers...