Obesity is an increasing problem worldwide, with a great unmet medical need [1]. Cholecystokinin (CCK) is a gastrointestinal hormone that could potentially be used as an anti-obesity drug, as evidenced by the lowering of food intake observed after administration to rodents [2, 3], pigs [4]...
CCK is an oligopeptide synthesized within the intestinal mucosa and released into the blood stream in response to the intake of a meal [1]. It is well-established that the main action of the hormone...doi:10.1007/978-3-642-76362-5_19Meyer-Wyss, B....
CCK(-like) peptides exert diverse physiological effects through binding their corresponding receptors, which are important members of the hormone-binding G-protein-coupled receptors. In this paper, CCK(-like) peptides and receptors are reviewed in a comparative way at levels of molecular structure,...
Dual RNA Sequencing Reveals Key Events When Different Giardia Life Cycle Stages Interact With Human Intestinal Epithelial Cells In Vitro The metabolic protein PCK1, the transcription factors HES7, HEY1 and JUN, the peptide hormone CCK and the mucins MUC2 and MUC5A are up-regulated in ... L ...
Growth-Regulatory Effects of Sensory Neuropeptides, Epidermal Growth Factor, Insulin, and Somatostatin on the Non-Transformed Intestinal Epithelial Cell Li... Substance P, neurokinin A (NKA), calcitonin gene-related peptide (CGRP), vasoactive intestinal peptide (VIP), and peptide YY (PYY) were test...
Secretin (S) is an enterogastrone which inhibits gastric acid secretion and gastric motility. Recently it was reported that S inhibited gastric emptying via a capsaicin (CAP)-sensitive vagal afferent pathway. However, the role of sensory... None - 《Regulatory Peptides》 被引量: 0发表: 1996...
CCK is also known to be a trophic hormone. We examined the relationship between gene expression of CCK and secretin mRNA and mucosal atrophy of the duodenum, using an experimental model of total parenteral nutrition (TPN) in conscious rats. In TPN group, CCK mRNA content decreased and mucosal...
This might have been a very important paper, which investigated the effects of traumatic brain injury on the levels of brain-gut hormone vasoactive intestinal peptide (VIP), cholecystokinin (CCK), and calcitonin gene-related peptide (CGRP) both in plasma and in jejunum in rats. Some very clear...
The gastrointestinal hormone cholecystokinin (CCK) has been proposed as having a number of physiologic actions. These include stimulation of gallbladder contraction and pancreatic protein secretion as well as regulation of gastric emptying, stimulation of intestinal motility, stimulation of insulin secretion...
It has been shown that peripheral exogenous administration of apelin increases the release of cholecystokinin (CCK), a well‐defined GI hormone that disturbs gastric emptying (GE), colon transit (CT) and small intestinal fasting motor pattern through CCK‐1 receptors expressed on vagal afferent ...