Ribavirin treatment reduced CCHF virus growth in liver and significantly decreased, but did not prevent, viremia. Despite a substantial viremia, infection of other organs including brain and heart was not detected in ribavirin-treated mice. A hepatotropic virus subpopulation with less neurovirulence ...
1 CCHF virus (Bunyaviridae Family and Nairovirus Genus) was first isolated from Russian soldiers in the Crimea in 1944 and source of transmission was described in 1967 by a Russian virologist.2 CCHF is endemic in Greece, Bulgaria, Kosovo, Albenia, Russia, South Africa, Iran and Turkey. ...
2008. Treatment of Crimean-Congo hemorrhagic fever. Antiviral Res, 78: 125-131. 10. Flick R. 2007. Chapter 4: Molecular Biology of the Crimean-Congo Hemorrhagic Fever Virus. In: Crimean-Congo Hemorrhagic Fever (O Ergonul, C A 345 Whitehouse ed.). Springer Netherlands, p 35-44. 11. ...
In addition, the Ministry of Health informed on May 25 received the report of Health Department of Hunan Province, Changsha City Public Health Center for treatment where a patient, clinical manifestations of symptoms such as cough, according to clinical manifestations, epidemiological investigation and ...
New research into the Crimean-Congo hemorrhagic fever virus (CCHFV), a tick-borne virus which causes a severe hemorrhagic disease in humans similar to that caused by Ebolavirus, has identified new cellular factors essential for CCHFV infection. This disc