GENE expressionPROTEIN foldingCELL growthBackground: Single synonymous codon mutations typically have only minor or no effects on gene function. Here, we estimate the effects on cell growth of ~ 200 single synonymous codon mutations in an operonic context by mutating almost all positions of ccdB,...
15. Reviewed in NATURE: Free Access to cDNA provides impetus to gene function work. 15 march 2001, p. 289. Generating directional cDNA libraries using recombination 16. Osamu Ohara and Gary F. Temple. Directional cDNA library construction assisted by the in vitro recombination reaction. Nucleic ...
Independently isolated CcdB resistance mutations were found to map in the gyrA gene; one of these mutants, A 462 , was sequenced and found to produce an amino acid substitution of Arg462to Cys (17). Separately, CcdB-tolerant mutations have been isolated in several genes: gyrA, groES (mopB...
近年来,消化科黄瑛教授团队多次创科研新高。2021年于国际权威期刊Nature Genetics(影响因子41.3分)发表重大科研成果“Gain-of-function variants in SYK cause immune dysregulation and systemic inflammation in humans and mice”,之后又分别在JCR...
多模态大模型框架DREAMLLM&通用泛化的手物交互算法GeneOH Diffusion 弋力 清华大学助理教授 弋力研究组提出了多模态大型语言学习框架DREAMLLM,首次实现了兼具多模态内容创作和理解的功能且相互促进的通用多模态大模型,并且是第一个原始数据级的完全自回归多模态大模型。...
Escherichia coli beta-galactosidase (beta-gal), encoded by the lacZ gene, has become an essential tool in studies of gene expression and function in higher... PR Odgren,MacKay, Carole A.,A Mason-Savas,... - 《Connective Tissue Research》 被引量: 42发表: 2006年 Quality evaluation of virtu...
- 《Gene An International Journal Focusing on Gene Cloning & Gene Structure & Function》 被引量: 1发表: 2016年 Method for improving the specificity of gene regulation in a transformed plant and construct. This invention seeks to improve the specificity of gene expression by targeting a specific ...
3 changes: 0 additions & 3 deletions 3 src/main/java/com/genersoft/iot/vmp/gb28181/bean/ParentPlatform.java Original file line numberDiff line numberDiff line change @@ -97,9 +97,6 @@ public class ParentPlatform { @Schema(description = "是否作为消息通道") private boolean asMessage...
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Mature B cells will typically expresseither immunoglobulin M (IgM) or immunoglobulin D (IgD) on their surface,邻家的IgD妹妹IgM,天真少女(IgM,IgD)andthis surface expression is critical to cell survival. Further, the combinationof the VDJ gene sequences is un...