In this study, we describe 19 different CC chemokine genes from the orange-spotted grouper, Epinephelus coioides, identified by the analysis of the spleen transcriptome. Multiple sequence alignment of the 19 CC chemokines showed that although two genes, EcSCYA115 and EcSCYA117, shared 80% amino ...
there is a growing recognition of the important roles of genetic factors in the occurrence and development of gynecological tumors. Genetic counseling is widely adopted in various aspects of precision medicine in tumor screening, diagnosis, treatment and prevention. From March t...
single-cell amplified genomes (SAGs). Vannier et al. estimated their SAG to be 64% complete using eukaryotic core genes from CEGMA. We estimated the quality of the SAG using BUSCO 4.0 and EukCC, which assessed the completeness to be 56.2% and 59.65% with a contamination of 7.4% and 14.0...
First, we looked for genes whose expression pattern is consistently associated with the expression pattern of DDR2 in human tumors since these may conceivably be members of signaling pathways that a tumor could use to escape DDR2 depletion. Using two human bladder cancer datasets, CNUH33and MSKCC...
Genomic context of CpGs utilized inGIMiCC.A–CThe methylation level of representative CpGs fromGIMiCClibraries at functionally relevant genes.D–FEnrichment analysis testing for the odds of the DMCs of the GBM L0 (D), AST L0 (E), and all other deconvolution layers (F) being in a CpG is...
Zhao, B. et al. TEAD mediates YAP-dependent gene induction and growth control.Genes Dev.22, 1962–1971 (2008). ArticleCASGoogle Scholar Ramos, A. & Camargo, F. D. The Hippo signaling pathway and stem cell biology.Trends Cell Biol.22, 339–346 (2012). ...
Clinical Trial Information(data fromhttps://clinicaltrials.gov, updated on 2024-05-22) NCT NumberRecruitmentConditionsSponsor/CollaboratorsStart DatePhases NCT01353625Completed Glioblastoma Multiforme|Squamous Cell Carcinoma of Head and Neck|Prostate Cancer|Ewing''s Osteosarcoma|Chronic Lymphocytic Leukemia|Neop...
The interaction between CC16 and FN1 was analyzed using the Search Tool for the Retrieval of Interacting Genes/Proteins (STRING) database (version 11.5;https://string-db.org/cgi/input.pl). Bronchial epithelial cell culture The 16-HBE cells were purchased from the American Type Culture Collectio...
Genome-wide gene expression analyses were then performed to identify the target genes of the tumour-suppressive miRNA. Results: Expression analysis identified 11 upregulated and 31 downregulated miRNAs. Gain-of-function analysis of the downregulated miRNAs revealed that miR-489 inhibited cell growth in...
E2F1 and CCND1 are two target genes of miR-93, and they are positively associated with chemoresistance of breast cancer Fig. 4: E2F1 and CCND1 are two direct targets of miR-93. The inhibitory effects of miR-93 on cell proliferation and cell cycle progression were abrogated by E2F1 and CC...