Cbz(Z) Protecting Group 概要 苄氧基羰基保护基(benzyloxycarbonyl, CbzまたはZ)、它经常用于通过形成氨基甲酸酯来保护胺基。在某些情况下,它还用于醇和苯酚上羟基的保护基。 于强碱条件下的酯水解条件・强酸性条件・亲核条件・弱的氢化物的还原条件耐受性好、可以通过接触还原条件进行脱保护。因此,可以与Fmoc保...
苄氧基羰基保护基 Cbz(Z) Protecting Group 概要 苄氧基羰基保护基(benzyloxycarbonyl, CbzまたはZ)、它经常用于通过形成氨基甲酸酯来保护胺基。在某些情况下,它还用于醇和苯酚上羟基的保护基。 于强碱条件下的酯水解条件・强酸性条件・亲核条件・弱的氢化物的还原条件耐受性好、可以通过接触还原条件进行脱保护。
N-Cbz-L-Threonine, with the chemical formula C15H19NO5 and CAS registry number 19728-63-3, is a compound known for its role as a protected form of L-threonine in peptide synthesis. This compound is characterized by the presence of a carbobenzyloxy (Cbz) protecting group on the threonine...
The selective deprotection of the amine protecting group enable us to synthesize several kanamycin A dimers linked at N-3 '' position in a straightforward way.Chen, GHPan, PChen, YMeng, XBLi, ZJTetrahedronChen, G.-H.; Pan, P.; Yao, Y.; Chen, Y.; Meng, X.-B.; Li, Z.-J. ...
Its basic structure consists of a tryptophan molecule with a carbobenzyloxy (Cbz) protecting group attached to the amino group. This compound is sparingly soluble in water, but it is soluble in organic solvents such as methanol and ethanol. Safety information regarding N-Cbz-D-Tryptophan is not...
The mechanism of action in peptide synthesis involves the selective removal of the Cbz protecting group under specific reaction conditions, allowing for the desired peptide bond formation. Storage ConditionsStore in a cool and dry place. View all ...
Chemical Synthesis: N-Cbz-L-Serine is commonly used in chemical synthesis as a protecting group for the amino acid serine. Its purpose in this field involves the temporary blocking of the amino group, allowing selective reactions to occur on other functional groups. The mechanism of action in ...
This compound, also referred to as N-Carbobenzyloxy-D-Alanine, is characterized by its carbobenzyloxy (Cbz) protecting group on the amino acid alanine. It is commonly used as a building block in the synthesis of peptides and peptidomimetics, providing stability and protection to the amino acid...
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This compound, also referred to as S-Carbobenzyloxy-L-cysteine, is characterized by its carboxybenzyloxy functional group. It is commonly used as a protecting group for the thiol group of cysteine in peptide synthesis, allowing for selective reactions and preventing unwanted side reactions. S-Cbz-...