DataSheetSDSCOAHNMRHPLC产品操作手册 产品介绍 生物活性 产品描述 ICG001 is a β-catenin/TCF-mediated transcription inhibitor that selectively blocks β-catenin/CBP interaction without interfering with β-catenin/p300 interaction. It specifically binds to CREB protein with an IC50 of 3 μM. ...
Cells or liver tissues were homogenized in cold RIPA buffer [50 mM Tris–HCl, 150 mM NaCl, 0.1% SDS, 0.1% Igepal in 0.5% sodium deoxycholate with 1 tablet of protease inhibitor cocktail and 1 tablet of phosphatase inhibitor (Roche) in 10 ml] on ice with a tissue homogenizer and the ly...