(g,h) Quantitative real-time polymerase chain reaction (PCR) showed that the genes Wnt1 and Wnt3a were induced in the heart of mice for 4 weeks after TAC (n = 10). (i,j) Quantitative real-time PCR revealed that the expression of brain natriuretic peptide (Bnp) and β-myosin ...
Bottom: coronal brain sections (10 μm) of CBP{HAT−} and wt mice corresponding to top panels and stained with cresyl violet showed no alterations in gross neuroanatomy. Abbreviations: Amyg, amygdala; CA1, pyramidal cell field of hippocampus; DG, dentate gyrus; CPu, caudate putamen. (C)...
Most major brain regions were affected by the CBP dependent reduction in size – e.g. the OB (Fig. 1d4), the corpus callosum (CC) (Fig. 1d5) and the hippocampus (Fig. 1d6) as demon- strated and measured in Magnetic Resonance (MR) im- ages of the mice. This corresponds well ...