Abstract In heart failure (HF) caused by hypertension, the myocyte size increases, and the cardiac wall thickens. A low-molecular-weight compound called ICG001 impedes β-catenin-mediated gene transcription, thereby protecting both the heart and kidney. However, the HF-preventive mechanisms of ICG...
CBP/β-catenin/FOXM1 provides a molecular target for precision therapy in triple negative breast cancer and could form a rationale for potential clinical trials. Keywords: triple negative breast cancer (TNBC); cancer stem cells (CSC); CREB-binding protein (CBP); forkhead box protein M1 (FOXM1...