In this process, epithelial cells lose cell-cell adhesions and acquire properties of mesenchymal cells, namely enhanced migratory and invasive abilities [8]. Many growth factors are involved in the initiation of EMT, including the insulin-like growth factor-I receptor (IGF-IR)/ligand system that ...
In this process, epithelial cells lose cell-cell adhesions and acquire properties of mesenchymal cells, namely enhanced migratory and invasive abilities [8]. Many growth factors are involved in the initiation of EMT, including the insulin-like growth factor-I receptor (IGF-IR)/ligand system that ...
Anti-NGF, FLAG, HA (rabbit), PY20 (phospho-tyrosine) antibodies were from Sigma (St Louis, MO, USA). Anti-POSH antibody was from Abnova (Taiwan). Anti-HA (mouse) was from Covance (Berkeley, CA, USA). Chemicals and reagents Anti-human recombinant NGF, camptothecin, anti-c-Myc aga- ...