目的:研究化学抗癌药物联合治疗小细胞肺癌的效果.方法:应用TAX,CBDCA与VP16联合治疗30例晚期小细胞肺癌.结果:CR 2例,PR 19例,总有效率达70%(21/30),且毒副反应较轻,无Ⅲ,Ⅳ级发生.结论:TAX,CBDCA与VP16三药联用治疗小细胞性肺癌临床疗效较显著.关键...
VP-16 was administered orally at the dose of 50 mg/m2 Days 1-14, HMM at the dose of 150 mg/m2 po Days 14-28. Therapy was repeated every 28 days for a total of 6 courses. In order to avoid severe leukopenia and delays in the treatment administration, G-CSF 5 μg/kg/day sc ...
Grade 1/11 fever was most frequently observed (79%). There were no grade III/IV IL-3 related adverse events. In conclusion, the IL-3 infusion following the CBDCA and VP-16 chemotherapy appears to reduce chemotherapy induced-thrombocytopenia with an acceptable toxicity 展开 ...