Caveolin-1 gene is coordinately regulated with the multidrug resistance 1 gene in normal and leukemic bone marrow. Leuk Res 2004;28:973-7.Pang,A. et al. (2004) Caveolin-1 gene is coordinately regulated with the multidrug resistance 1 gene in normal and leukemic bone marrow. Leuk. Res.,...
本实验 乳腺癌及雌激素受体信号通路基因芯片(HS-020(人)) 室前期工作中, 利用基因捕获(gene trapping)技术得 购自上海康成公司; 蛋白质 G 琼脂糖珠(Protein G 到稳定传代的 Cav-1 单倍不足细胞株 MCF10A-ST1, Agarose, Fast Flow), 酪氨酸磷酸化蛋白抗体(4G10, 发现Cav-1 表达降低可以激活细胞内雌激素...
猪小窝蛋白1(caveolin-1)的基因结构及在 各组织中的表达分析 王翀①, 梅盈洁①, 李莉①, 莫德林②, 李加琪①, 张豪①, 田兴国①, 陈瑶生②* ①华南农业大学动物科学学院, 广州 510642;②中山大学生命科学学院, 广州 510006 * 联系人, E-mail: chyaosh@mail.sysu.edu.cn 收稿日期: 2007-10-16; 接受...
家鸽caveolin-1 基因全长 cdna 的克隆, 序列和组织表达分析 cloning and characterization of caveolin-1 gene in pigeon, columba livia domestica 窖蛋白(Caveolin)是一类构成细胞膜上胞膜窖主要结构的标志蛋白,由Caveolin基因家族编码而成.Caveolin-1基因是Caveolin基因家族的成员之一.该实验采用RT-PCR与RACE(rap......
Meth⁃ods The introduced caveolin-1 gene knockout mice were reared in the SPF laboratory and genomic DNA was extracted from mouse tail tissue by the method of boiling lysis. According to the primer sequences provided by the Jackson Laboratory of America for polymerase chain reaction ( PCR) ...
In this study, we show that electroporation-mediated gene transfer of plasmids expressing Cav-1 can protect from bleomycin-induced pulmonary fibrosis through downregulation of inflammasome activity in the lung epithelium. We investigated inflammasome activity in lung tissues from IPF patients and control ...
Caveolin-1 gene and polypeptide encoded thereby and methods of use thereofThe invention relates to compositions comprising caveolin polypeptides and nucleic acids, and methods of use thereof. The invention is useful in the treatment of non-steroid dependent carcinoma, especially for treatment of ...
Caveolin-1 gene disruption promotes mammary tumorigenesis and dramatically enhances lung metastasis in vivo. Role of Cav-1 in cell invasiveness and matrix metalloproteinase (MMP-2/9) secretion. : J Biol Chem. 2004, 279(49):51630-46. Racine C, Belanger M, Hirabayashi H, et al. Reduction of...
博士学位论文 中文摘要 结果:1.人前列腺癌PC-3和PC-3m细胞中均有Caveolin-lmRNA 的表达,PC-3m细胞中的Caveolin-I表达水平明显高于PC-3细胞, 两者有显著性差异(尺0.05)。 2.人前列腺癌PC-3和Pp3m细胞中均有Caveolin-I蛋白质表 达,PC一3m细胞中Caveolin-1蛋白质表达量较PC-3细胞增加,两者 有显著性差异(尺...
A gene on chromosome 7q31.1 that encodes caveolin 1, the main scaffolding protein of caveolae plasma membranes in most cells. Caveloin 1 links integrin subunits to the tyrosine kinase FYN, an early step in coupling integrins to the Ras-ERK pathway which drives cell cycle progression; CAV1 is...