Zika virus (ZIKV) infection in pregnant women has been established as a cause of microcephaly in newborns. Here we test the hypothesis that neurodevelopmental stages when the brain is undergoing rapid growth are particularly vulnerable to the effects of ZIKV infection. We injected ZIKV intracranially...
Microcephaly is having a head circumference well below average. The child's brain stops growing as it should, either while the baby is in the mother's womb or in the first few years of life. How Does a Baby Get Microcephaly? Your doctor may not be able to tell you why this happened...
Most cytomegalovirus (CMV) infections are asymptomatic, and clinically evident infection is observed at birth in about 10% of congenitally infected infants. Clinical signs of congenital infection include microcephaly, jaundice, hepatosplenomegaly, petechiae or purpura, thrombocytopenia, and hepatitis. The ...
it is important to recognize that the vast majority of premature infants, even those born very prematurely, do not suffer from cerebral palsy. There have been many advances in the field of neonatology (the care and study of problems affecting newborninfants) that have enhanced the survival of ...
Zika virus (ZIKV) can cause microcephaly in the fetus. However, its effects on body growth and the development of children with postnatal ZIKV infection are largely unknown. To examine this, we intraperitoneally challenged mouse pups with ZIKV. Infection causes an irreversible growth delay and defic...
undergo cellular senescence as a result of VPA. The researchers also identified p19Arfas the specific molecule that caused this VPA-induced senescence. Although VPA exposure during pregnancy still resulted in other abnormalities, the scientists found that it no longer produced microcephaly (a small hea...
Some infections, such as cytomegalovirus (CMV), can cause congenital deafness and other problems in the baby. If a pregnant woman contracts the Zika virus (also called Zika fever), it may cause a birth defect called microcephaly (small head). On the other hand, if the fever accompanies a ...
Small head (microcephaly) Seizures Hearing loss Pneumonia Liver inflammation (hepatitis) Developmental delay Motor delay Vision problems In severe cases, CMV can lead to a miscarriage. Symptoms of CMV with HIV If you also have advanced HIV, CMV can affect different parts of your body. You could...
Small head (microcephaly) Seizures Hearing loss Pneumonia Liver inflammation (hepatitis) Developmental delay Motor delay Vision problems In severe cases, CMV can lead to a miscarriage. Symptoms of CMV with HIV If you also have advanced HIV, CMV can affect different parts of your body. You could...
The majority of infections, however, do not cause visible abnormalities in mothers and infants. In this study, we induced ZIKV infection in fetal pigs. Similar to humans, ZIKV caused prolonged (for months) infection in porcine fetuses. Some newborn animals also developed several abnormalities ...