Naked grains with low glume coverage have dramatically increased threshing efficiency and seed quality. Here, we demonstrate that GC1 (Glume Coverage 1), encoding an atypical G protein γ subunit, negatively regulates sorghum glume coverage. Naturally truncated variations of GC1 C-terminus accumulate ...
However, several technical and scientific issues remain before these proof-of-principle demonstrations are advanced to effect vector population suppression. The development of a Y-drive has so far proven difficult because of the complete transcriptional shut down of the sex chromosomes during meiosis, w...
First, mRNA expression of the proinflammatory cytokines IL-1β and TNF-α was investigated following stimulation with PFF and LPS. Both PFF and LPS substantially increased IL-1β and TNF-α mRNA expression (Fig. 1a). These data suggested that PFF stimulated an acute inflammatory response in ...
IGFBP-4 protein levels in calvaria of transgenic (OC-BP4) mice as measured by Western ligand blot were increased 25-fold over the endogenous level. Interestingly, levels of IGFBP-5 were decreased in the OC-BP4 mice, possibly because of a compensatory alteration in IGF-1 action. Morphometric...
of complex dietary components [17,18], as well as the development and activity of the host immune system [19,20,21]. For example, laboratory experiments have demonstrated that increased fungal diversity in the GM can reduce the severity of diseases such as colitis in captive mice (Mus ...
We then examined the immune infiltrate in pancreata of RIP-NP+/IL6+ double Tg mice at 5 weeks of age, i.e. prior to the development of hyperglycemia, and found that co-expression of NP and IL6 increased the amount of CD11b+ cells in the immune infiltrate, but did not cause ...
After a binding time of 2 h, the beads were washed three times with lysis buffer and boiled in 2× Laemmli containing 0.1 M DTT for protein denaturation. For endogenous co-immunoprecipitation, the binding time was increased to 16–20 h. Western blot Protein samples were separated by...
These variants impair ligand binding and G protein-dependent signalling in cells. Transgenic mice harbouring a loss of function GPR10 variant found in an individual with obesity, gain excessive weight due to decreased energy expenditure rather than increased food intake. This evidence supports a role...
The overall density of the FK2-immunoreactive bands was significantly increased by BSO treatment compared with control saline treatment; the density was 191.1 ± 8.4% of the control value (Fig. 4B). On the other hand, the overall level of the rMRP2 protein was decreased by BSO treatment and...
molecular causes for the increased stickiness of cooked non-glutinous rice 系统标签: glutinous rice cooked molecular protein non ContentslistsavailableatScienceDirect CarbohydratePolymers journalhomepage:.elsevier/locate/carbpol Molecularcausesfortheincreasedstickinessofcookednon-glutinousriceby enzymatichydrolysisof...