Elevated levels of B12 are rare and often caused by disease, most commonly decreased liver function or diseases of the blood.According to the Mayo Clinic, "Vitamin B12, or cobalamin, helps nerve cells, red blood cells and is used in the creation of DNA." Over-production of Vitamin B12 can...
Biochemical studies in all patients did not show methylmalonic acidemia or hyperhomocysteinemia but revealed elevated vitamin B12 levels. Trio exome sequencing of the proband and his parents revealed a maternally inherited novel variant in HCFC1 designated as c.1781_1803 + 3del26insCA (NM_005334)...
A study including over 500 adults found that vitamin D deficiency was linked to greater fat mass, but only in those with elevated parathyroid hormone (PTH), suggesting the cause may lie in controlling that level. Skeletal disease Vitamin D enhances the absorption of dietary calcium by 30%-40%...
Vitamin B12 deficiency can also contribute to depression, and affects one in four people. Last but not least, make sure you get enough sleep. The link between depression and lack of sleep is well established. Of the approximately 18 million Americans with depression, more than half of them ...
Vitamin deficiencies:Deficiencies of thevitaminsB12 and folate, as well as other B vitamins, can cause damage to the nerves. Autoimmune neuropathy:Autoimmune diseases such asrheumatoid arthritis, systemiclupus, andGuillain-Barre syndromecan cause neuropathies. ...
Nutritional testing may be considered to rule out Vitamin B and Vitamin D deficiencies. Testing for elevated levels of heavy metals (lead, mercury, copper, zinc, chromium) as well as Lyme titer can be useful. diagnostic testing- The standard tests over the years has been nerve conduction studi...
Iron deficiency anemia: A condition where there's a lack of iron in the body, leading to a decreased production of hemoglobin and red blood cells. Vitamin B12 deficiency anemia: Deficiency in vitamin B12 can lead to the production of abnormally large red blood cells, which are not as efficie...
These will be performed in order to test one’s levels of electrolytes and creatinine, and afull blood count (FBC)test will be carried out to detect infection and anemia. Tests will also be performed to establish one’s levels of nitrogen,bilirubin, transferrin vitamin B12 and folic acid. ...
β-Propeller protein-associated neurodegeneration (BPAN) is a rare X-linked dominant disease, one of several conditions that manifest with neurodegeneration and brain iron accumulation. Mutations in the WD repeat domain 45 (WDR45) gene encoding WIPI4 lea
Illness: Chronic illnesses like diabetes,alcoholism,cancer, andvitamindeficiencies (for example, B12 deficiency causingpernicious anemia) may also result innerve painthat often affects both legs. There are some illnesses that cause leg weakness that may be associated with complaints of leg pain, inclu...