Cerebellar vermis hypoplasia, aqueductal stenosis, obstructive hydrocephalus, and pontine hypoplasia were variably associated. The second pattern observed in one fetus was characterized by callosal dysgenesis, reduced white matter, and pontine hypoplasia. The identification of these features should alert ...
X-ray findings at birth for most subjects resembled the changes seen in neonatal hyperparathyroidism. Subjects 1–5 had complete recovery by age 2 years, whereas subject 6 had hydrocephalus and chest expanders placed at 7 months of age. However, her skeletal abnormalities also gradually improved ...
convulsions, spasticity,cerebral palsy, deafness, and severely impaired vision. The infant's head may be abnormally small (microcephaly) or abnormally large due to increased pressure on the brain (hydrocephalus).
If fetuses survive, such injury may manifest as arthrogryposis, hydranencephaly, porencephaly, microencephaly, hydrocephalus, or encephalomyelitis at term. The earlier in gestation that fetal infection occurs, the more severe the lesions, reflecting the large population of vulnerable cells and lack ...
The child was ultimately born with a number of defects, including spina bifida and hydrocephalus. The woman claimed that the physicians who prescribed the Depakote had not warned her of the dangers of birth defects arising from its use during pregnancy and that the failure to warn her of these...