Microscopically, calcium oxalate (CaOx) crystals were observed more frequently in GDs and FNDs with MPEF (100% and 88.5%, respectively) than in those without MPEF (p<0.001). These differences were particularly significant for CaOx crystals>100渭m. In GD cases, large CaOx crystals were ...
What causes uric acid crystals in urine? They can be found in normal urine whencaused by a protein-rich diet, which increases uric acid in the urine. They can also be caused by kidney stones, gout, chemotherapy, or tumor lysis syndrome. Symptoms of kidney stones include severe abdominal, ...
They form when the urine contains morecrystal-formingsubstances (eg, calcium, oxalate and uric acid) than can be diluted by the fluid in the urine and/or when the urine does not have the substances that prevent crystals from sticking together. The lifetime risk for kidney stones among adults...
Many have demonstrated that oxalate ions as well as calcium oxalate crystals promote renal tubular injury (manifested in vivo as an increase in urinary enzymes) and much recent attention has focused on the generation of free radicals as a potential mechanism by which this injury occurs [9, 10,...
Inflammatory exudates of white blood cells and proteins, red blood cells from hemorrhage, sloughed epithelial cells, fibrin, calcium oxalate crystals, and calici-like viral particles may also become trapped if present in urine at the time of plug formation. In addition to intraluminal obstruction,...
The Clinical Chemistry of Oxalate Metabolism This chapter discusses the clinical chemistry of oxalate metabolism. Disorders of oxalate metabolism that cause tissue deposition of insoluble calcium oxalate (oxalasis) or excessive excretion in urine (hyperoxaluria) has been increasing... MF Laker - 《Advanc...
If there are too many oxalates in the kidneys, they can combine with other minerals, primarily calcium, to form calcium oxalate crystals that become calcium oxalate kidney stones. Some people are predisposed to having too much calcium in the urine, which will interact with the oxalates more ...
In an extension of this work we recently reported that addition of dissolved urate promoted the nucleation, bulk deposition and aggregation of CaOx crystals generated from undiluted urine in response to increasing the oxalate concentration2. Although we have since demonstrated that adding the urate ...