Cataplexy is a neurological disorder that causes people to lose muscle tone and strength for a short time, usually in response to...
Slack face eyes Wobbly walk Tongue They may have mild weakness in their muscles for hours after the episode, too. What Causes It? Experts are still looking into that question. But most people who have narcolepsy with cataplexy show a sign that doctors can spot with tests: a loss ofbraince...
Thinking outside the box: cataplexy without narcolepsyCataplexyNarcolepsyNiemann-Pick type C DiseaseAngelman SyndromeNorrie DiseasePrader-Willi SyndromeCataplexy is a transient loss of muscle tone that can be triggered by emotions such as laughter, excitement or fear. Other causes of cataplexy include...
Deficiency of the neuropeptide orexin in the hypothalamus is one of the causes of this symptom7 and activation of the NAc and the prefrontal cortex is thought to be an upstream trigger9,10. Studies have also shown that the amygdala is a key brain structure involved in the occurrence of ...
The hypothesis that a targeted immune-mediated or autoimmune attack causes the specific degeneration of hypocretin neurons arose mainly through the discovery of genetic associations, first with the HLA-DQB1*06:02 allele and then with the T-cell receptor α locus. Guided by these genetic findings ...
In establishing a diagnosis a comprehensive history to exclude other causes of EDS, including poor sleep habits, is essential. Primary sleep related conditions such as sleep apnoea should be excluded. Investigations for confirmation of the diagnosis include Actigraphy, Polysomnography (PSG), Multiple ...
The hypothesis that a targeted immune-mediated or autoimmune attack causes the specific degeneration of hypocretin neurons arose mainly through the discovery of genetic associations, first with the HLA-DQB1*06:02 allele and then with the T-cell receptor α locus. Guided by these genetic findings ...
d. cataplexy. Sleep Disorders: Some sleep disorders keep one up when one wants to sleep, while other sleep disorders knock one down while one is awake. There can be various medical causes for these involving neural problems, o...
Meditation can be understood as a procedure that induces a state of attentive relaxation. Empirical studies have found that a meditative state is characterized by the theta brain waves. Answer and Explanation: The correct solution to...
The condition is believed to result from autoimmune destruction of hypocretin (HCRT) neurons, although direct evidence is lacking and mere Hcrt gene inactivation causes full-blown narcolepsy in mice. Here we show that the expression of another hypothalamic neuropeptide, QRFP, is lost in mouse ...