The meaning of CATABOLISM is degradative metabolism involving the release of energy and resulting in the breakdown of complex materials (such as proteins or lipids) within the organism.
Ageing has been defined as a global decline in physiological function depending on both environmental and genetic factors. Here we identify gene transcripts that are similarly regulated during physiological ageing in nematodes, zebrafish and mice. We observe the strongest extension of lifespan when impai...
Embryonic dormancy is defined as a set of blocks imposed upon a process(es) cardinal for growth. In apple seeds, all these blocks are removed as a result o... Stanisław Lewak - 《Acta Physiologiae Plantarum》 被引量: 36发表: 2011年 Antifungal compounds redirect metabolic pathways in yeast...
Protein catabolismis of crucial importance for musclehomeostasis, being responsible for the clearance of damaged or aged proteins as well as for the elimination of molecules endowed with regulatory functions, such ascyclinsand their inhibitors. However, up-regulation of protein breakdown exceedingprotein ...
Current understanding of the carbon cycle in methanogenic environments involves trophic interactions such as interspecies H2 transfer between organotrophs and methanogens. However, many metabolic processes are thermodynamically sensitive to H2 accumulati
Cancer cells rewire metabolism to favour the generation of specialized metabolites that support tumour growth and reshape the tumour microenvironment1,2. Lysine functions as a biosynthetic molecule, energy source and antioxidant3–5, but little is known
Cancer cells rewire metabolism to favour the generation of specialized metabolites that support tumour growth and reshape the tumour microenvironment1,2. Lysine functions as a biosynthetic molecule, energy source and antioxidant3–5, but little is known
This oxidative ring opening sequence resembles the pathway for camphor degradation by the soil diphtheroid, Mycobacterium rhodochrous, that ultimately leads to isoketocamphoric as the last defined metabolite that contains all 10 carbons of the original bicyclic nucleus. Studies with both cell cultures ...
s threshold H2concentration at which ∆G becomes 0 kJ/mol. ∆G values are calculated as the ∆Greaction+ (mol ATP generated/mol reaction)*∆GATPsynthesis(see details below). The H2partial pressure range at which each metabolism is thermodynamically favorable is shown at the top (...
PDK4 is a key enzyme involved in regulation of glucose and fatty acid metabolism as well as tissue homeostasis, while its overexpression inactivates the PDH complex by phosphorylating the targets and contributes to metabolic flexibility. We assessed the influence of PDK4 expression by transducing a ...