[6]Involvement of mitochondria and caspase-3 in ET-18-OCH3-induced apoptosis of human leukemic cells.Gajate C,Santos-Beneit AM,Macho A,et al.International Journal of Cancer.2000 [7]Mechanisms of cyclosporine A-induced apoptosis in rat hepatocyte primary cultures.Grub S,Persohn E,Trommer WE,e...
In addition, proliferation of the A549 cells transfected with caspase-3 siRNA was not different from their control groups. Overexpression of caspase-3 in MCF-7 cells reduced the expression of paxillin while the cells remained viable. In addition, the caspase-3 overexpressing MCF-7 cells possessed...
GreenNuc™活细胞Caspase-3活性检测试剂盒(GreenNuc™ Caspase-3 Assay Kit for Live Cells)是一种使用新型的具有细胞膜通透性的Caspase-3/7绿色荧光底物来检测活细胞中Caspase-3/7活性的试剂盒,可用于实时检测活细胞的凋亡情况。 Caspase (Cysteine-requiring Aspartate Protease)是一个在细胞凋亡过程中起重要作用的...
Caspase-3 (also know as CPP32, Yama and apopain) is a major member of the caspase-family of cysteine proteases. Caspase-3 exists in cells as an inactive 32 kDa proenzyme. During apoptosis procaspase-3 is processed at aspartate residues by self-proteolysis and/or cleavage by upstream caspase...
GreenNuc™活细胞Caspase-3活性检测试剂盒(GreenNuc™ Caspase-3 Assay Kit for Live Cells)是一种使用新型的具有细胞膜通透性的Caspase-3/7绿色荧光底物来检测活细胞中Caspase-3/7活性的试剂盒,可用于实时检测活细胞的凋亡情况。 Caspase (Cysteine-requiring Aspartate Protease)是一个在细胞凋亡过程中起重要作用的...
1. 合理的凋亡诱导处理方式:设置药物诱导时间和浓度梯度预实验,以确定特定细胞系中药物诱导 caspase-3 活化的最佳条件,并用 staurosporine #9953(1μM for 3hours)或 etoposide #2200(25μM for 5 hours)处理 HeLa,NIH/3T3 或 C6 cells 作为 cleaved caspase-3 的阳性参照。
1. 合理的凋亡诱导处理方式:设置药物诱导时间和浓度梯度预实验,以确定特定细胞系中药物诱导 caspase-3 活化的最佳条件,并用 staurosporine #9953(1μM for 3hours)或 etoposide #2200(25μM for 5 hours)处理 HeLa,NIH/3T3 或 C6 cells 作为 cleave...
GreenNuc™活细胞Caspase-3活性检测试剂盒(GreenNuc™ Caspase-3 Assay Kit for Live Cells)是一种使用新型的具有细胞膜通透性的Caspase-3/7绿色荧光底物来检测活细胞中Caspase-3/7活性的试剂盒,可用于实时检测活细胞的凋亡情况。 Caspase (Cysteine-requiring Aspartate Protease)是一个在细胞凋亡过程中起重要作用的...
《Long non-coding RNA AGAP2-AS1 promotes the proliferation of glioma cells by sponging miR-15a/b-5p to upregulate the expression of HDGF and activating Wnt/β-catenin signaling pathway》 作者:YonghuiZhengaSumeiLubYanhongXucJiaolinZheng 期刊:Int. J. Biol. Macromol. 影响因子:4.784 PMID:30684575...
cells, murine primarycellsand mouse model, while the loss ofcaspase-3or inhibiting apoptosis markedly enhances these immune signalings. Furthermore, caspase-3 can mediate the cleavage of NF-κB members p65/RelA, RelB, and c-Rel via its protease activity. And the caspase-3-resistant p65/RelA...