IL-1尾-converting enzyme (ICE; caspase-1) is the intracellular protease that cleaves the precursors of LI-1尾 and IL-18 into active cytokines. In the present study, the effect of ICE deficiency was evaluated during experimental colitis in mice. In acute dextran sulfate sodium-induced colitis,...
产品名称:Caspase 1活性检测试剂盒(分光光度法) 规格50Assays 英文名称:Caspase 1 Activity Assay Kit(Colorimetric Method) 货号:E-CK-A381 检测原理 Caspase 1也称interkeukin 1β conberting enzyme (ICE),是caspase家族中 可以剪切IL-1β前体蛋白或IL-18前体产生相应成熟的细胞因子的caspase。Caspase 11可以剪...
part of the active enzyme. Active caspase 1 contains two heterodimers of p20 and p10. It interacts with another CARD domain containing protein called PYCARD (or ASC) and is involved in inflammasome formation and activation of inflammatory processes.Caspase 1 has been shown to induce cell necros...
Caspase 1也称interkeukin 1b conberting enzyme(ICE),有时被写作caspase-1或caspase 1,是caspase家族中*可以剪切IL-1b前体蛋白或IL-18前体产生相应成熟的细胞因子的caspase。Caspase 11可以剪切45kD的caspase 1前体蛋白,产生20kD和10kD的片段,这两个片段可以形成异源二聚体(heterodimer),并进一步由两个异源二聚...
重组人Caspase-1蛋白蛋白产品,又称Caspase-1, CASP-1, Interleukin-1 beta convertase, IL-1BC, IL-1 beta-converting enzyme, p45.其对应NCBI基因号为834,NCBI基因别称为CASP1;该基因种属来源为人源,对应Accession号为NP_150634.1.该蛋白产品又称Active Human Caspase-1, Active Caspase-1, Caspase-1 Enzyme,...
Caspase 1又称Interkeukin 1conberting enzyme (ICE)或caspase-1,是唯一可以剪切IL-1前体蛋白或IL-18前体产生相应成熟细胞因子的Caspase家族成员。Caspase 1通过剪切Bcl-XL来调节细胞凋亡,并通过对一些细胞因子前体的剪切来调控相关免疫反应。Caspase 1活性检测试剂盒(比色法)(Caspase 1 Colorimetric Assay Kit)的...
Caspase 1活性检测试剂盒(Caspase 1 Activity Assay Kit)是采用分光光度法检测细胞或组织裂解液中Caspase 1酶活性或纯化的Caspase 1酶活性的试剂盒。Caspase(Cysteine-requiring Aspartate Protease)是一个在细胞凋亡过程中起重要作用的蛋白酶家族。Caspase 1 也称interkeukin 1b conberting enzyme(ICE),有时被写作...
Caspase 1活性检测试剂盒(Caspase 1 Activity Assay Kit)是采用分光光度法检测细胞或组织裂解液中caspase 1酶活性或纯化的caspase 1酶活性的试剂盒。Caspase (Cysteine-requiring Aspartate Protease)是一个在细胞凋亡过程中起重要作用的蛋白酶家族。Caspase 1也称interkeukin1β conberting enzyme (ICE),有时被写作cas...
The hydrolysis of peptide substrates by caspase-1 (interleukin-1beta-converting enzyme), caspase-4 and caspase-8 is inhibited by PI9 in a time-dependent manner. The rate of reaction of caspase-1 with PI9, as well as the rate of substrate hydrolysis of the initial caspase-PI9 complex, ...