产品名称:Caspase 1活性检测试剂盒(分光光度法) 规格50Assays 英文名称:Caspase 1 Activity Assay Kit(Colorimetric Method) 货号:E-CK-A381 检测原理 Caspase 1也称interkeukin 1β conberting enzyme (ICE),是caspase家族中 可以剪切IL-1β前体蛋白或IL-18前体产生相应成熟的细胞因子的caspase。Caspase 11可以剪...
Caspase-1活性测定试剂盒规格 抚生 FS-X10203 英文名称Caspase1ActivityAssayKit 别名Caspase1活性测定试剂盒 Caspase-1是*可剪切IL-1b和IL-18前体产生活性细胞因子的caspase。Caspase-11剪切45kD的caspase-1前体蛋白产生20kD和10kD片断,这两个片断可以形成异源二聚体,并进一步形成四聚体。
细胞中caspase-1浓度较低,需要将caspase-1募集到炎症小体才能促进其二聚化和激活。随后CDL中的裂解导致caspase-1从炎症小体中解离,并使游离的p20/p10 caspase-1二聚体不稳定。 体外表达的重组caspase-1 p20/p10不需要炎症小体来获得活性,...
Caspase 1 活性检测试剂盒(Caspase 1 Activity Assay Kit)是采用分光光度法检测细胞或组织裂解液中caspase 1酶活性或纯化的caspase 1酶活性的试剂盒。 Caspase(Cysteine-requiring Aspartate Protease)是一个在细胞凋亡过程中起重要作用的蛋白酶家族。Caspase 1也称interkeukin 1b conberting enzyme(ICE),有时被写作ca...
Caspase 1 activity influences juvenile Batten disease (CLN3) pathogenesis. Mutations in CLN3 (ceroid lipofuscinosis 3; Cln3Δex7/8) manifest as a progressive neurodegenerative disorder commonly referred to as juvenile Batten disease. Based on the ability of caspase 1 to cleave a large number of ...
Caspase 1 活性检测试剂盒(Caspase 1 Activity Assay Kit)是采用分光光度法检测细胞或组织裂解液中caspase 1酶活性或纯化的caspase 1酶活性的试剂盒。 Caspase(Cysteine-requiring Aspartate Protease)是一个在细胞凋亡过程中起重要作用的蛋白酶家族。Caspase 1也称 ...
Although caspase-1 is a key participant in inflammation, there is no sensitive assay to measure its enzymatic activity in real time in cells or animals. Here we describe a nanosensor for caspase-1 ratiometric measurements, consisting of a rhodamine-labeled, caspase-1 cleavable peptide linked to...
Cryopyrin-induced interleukin 1β secretion in monocytic cells: enhanced activity of disease-associated mutants and requirement for ASC. J. Biol. Chem. 279, 21924–21928 (2004). CAS PubMed Google Scholar Gattorno, M. et al. Pattern of interleukin-1β secretion in response to lipopolysaccharide...
ChemicalBook 为您提供CASPASE 1 Activity Detection Kit|CASPASE 1 活性检测试剂盒的供应商,生产企业,生产厂家。
Riboflavin was further confirmed to disrupt the activity of caspase-1, and it also inhibited the AIM2, NLRC4, and non-canonical inflammasomes. Therefore, riboflavin has both an antioxidant effect and an anti-inflammasome property that regulates the inflammatory response....