Casein kinase-II regulates NMDA channel function in hippocampal neurons. Nat Neurosci 2: 125- 132, 1999.Lieberman DN, Mody I (1999) Casein kinase-II regulates NMDA channel function in hippocampal neurons. Nat Neurosci 2:125-132.Lieberman, D.N. & Mody, I. Casein kinase-II regulates NMDA ...
Protein kinase CK2 (formerly casein kinase 2) is recognized as a central component in the control of the cellular homeostasis; however, much remains unknown regarding its regulation and its implication in cellular transformation and carcinogenesis. Moreover, study of CK2 function and regulation in a...
Several second-messenger-regulated protein kinases have been implicated in the regulation of N-methyl-D-aspartate (NMDA) channel function. Yet the role of calcium and cyclic-nucleotide-independent kinases, such as casein kinase II (CKII), has remained unexplored. Here we identify CKII as an end...
别名Casein kinase 2 beta polypeptide; casein kinase IIβ; Casein kinase II subunit beta; CK II beta; CK2B; CK2N; CSK2B; CSK2B_HUMAN; CSNK 2B; CSNK2B; G5A; MGC138222; MGC138224; Phosvitin; Protein G5a. 抗体来源Rabbit 克隆类型Polyclonal ...
Targeting casein kinase II restores Ikaros tumor suppressor activity and demonstrates therapeutic ef fi cacy in high-risk leukemia. Blood 2015; 126: 1813–1823. 18 Silva A, Yunes JA, Cardoso BA, Martins LR, Jotta PY, Abecasis M et al. PTEN posttranslational inactivation and hyperactivation of ...
The function of a limited number of substrates, generally nuclear transcription factors, is changed by phosphorylation. The kinase may be involved in regulation of cell proliferation. The holoenzyme (130 kDa) is a heterotetramer consisting of two α (catalytic) and two β (regulatory) subunits in...
Hanif IM, Shazib MA, Ahmad KA, Pervaiz S . Casein kinase II: an attractive target for anti-cancer drug design.Int J Biochem Cell Biol2010;42: 1602–1605. ArticleCASGoogle Scholar Duncan JS, Litchfield DW . Too much of a good thing: the role of protein kinase CK2 in tumorigenesis and...
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Here, using a genetic screen, we identify casein kinase II (CK2) as a factor required for piRNA pathway function. We show that CK2 is required for the localization of PRG-1 and for the proper localization of several factors that comprise the ‘upstream sequence transcription complex’ (USTC)...
2003. Phosphorylation of FREQUENCY protein by casein kinase II is necessary for the function of the Neurospora circadian clock. Mol. Cell. Biol. 23: 6221.Yang Y, Cheng P, He Q, et al. Phosphorylation of frequency protein by casein kinase Ⅱ is necessary for the function of the Neurospora ...