CRISPRSSCIENTIFIC knowledgeELECTRONIC encyclopediasCIRCADIAN rhythmsGENOME editingRapid developments and methodological divides hinder the study of how scientific knowledge accumulates, consolidates and transfer
A. et al. Parallel CRISPR-Cas9 screens identify mechanisms of PLIN2 and lipid droplet regulation. Dev. Cell 58, 1782–1800.e10 (2023). Article CAS PubMed PubMed Central Google Scholar Corsello, S. M. et al. Discovering the anticancer potential of non-oncology drugs by systematic viability...
CRISPR Case Study 測試 CRISPR 點擊卡片即可翻轉 👆 Clustered Regularly Interspaced Short Palindromic Repeats 點擊卡片即可翻轉 👆 Hayley5955 Top creator on Quizlet · 1年前建立 學生們也學習了 單詞卡學習集 學習指南 BIOL 103- Chapter 1 Key terms...
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In a non-conventional track, scientists at Oak Ridge National Laboratory used their expertise in quantum biology, artificial intelligence, and bioengineering to improve how CRISPR Cas9 genome editing tools work on organisms like microbes that can be modified to produce N guyen BMC Bioinformatics (...
Multiplexing microbes on the PacBio Sequel: Feasibility, benefits, and recent developments (Tech Note) This study proves the feasibility of multiplexing and highlights the key advantages of the PacBio Sequel platform as compared to its predecessor, the RSII. Download Now Detection of Previously Uni...
In this study we investigated EHMT1 protein truncation in the HEK293T cell line which is well characterized, can be routinely cultured in the laboratory, and is amenable to CRISPR gene editing. Therefore, in order to create EHMT1 haploinsufficiency, a hallmark of Kleefsta syndrome, the EHMT1_...
To assist in the process, the CRISPR/Cas9 system has been developed to create insertions and deletions in chosen genes allowing for the alteration and analysis of phenotypic changes resulting from the targeted mutations (Bassett et al., 2013). This is significant for determining the role of ...
These haplotype aware assemblies can be used to study the dif- ferential loss of genes between haplotypes, which often is the result of whole genome duplication events [255]. Before haplotype aware assemblies, we relied on consen- sus sequences with a single allele per locus, developed from ...