病例对照研究 (Case-Control Study) ? 内容 概述 设计和实施 资料的整理和分析 优点和局限性 概 述 ?一、病例对照研究的定义 选择患有某特定疾病的病人作为病例,以不患有该病但具有可比性的个体作为对照,调查他们发病前对某个(些)因素的暴露情况,比较两组中暴露率和暴露水平的差异,研究该疾病与这个(些)因素...
Edwardes MD: Sample size requirements for case-control study designs. BMC Med Res Methodol 2001, 1:11.Edwardes M. Sample size requirements for case-control study designs: correction. BMC Med Res Methodol. 2002; 2:16.EDWARDES, E. (2001). Sample size requirements for case-control study ...
case-control-study Case-ControlStudy （病例对照研究）1.BasicConcepts Astudystartswiththeidentificationofpersonswiththediseaseofinterestandacontrolgroupofpersonswithoutthedisease,tomeasuretheassociationbetweentheexposureandthediseasebycomparingthediseasedandnon-diseasedwithregardedtohowfrequentlytheexposurepresent.Exposure ...
22、ng controls,Case-Control Study,Advantages: Cheaper, quicker Allows to study rare diseases Smaller sample size Allows to study several exposures at the same time,Case-Control Study,Disadvantages: Does not allow studying several diseases at the same time Risk of disease cannot be estimated directl...
1、巢式病例对照研究（套迭式；嵌入式）（nestedcase-controlstudy）：通过队列 研究，确认随访时发生的病例，作为病例组，以同一队列的未发病者为对照。优点：（1）暴露资料在发病或死亡前获得，时间顺序清楚，无回忆偏倚。（2）两组可比性好（3）可提高统计及检验效率 暴露率高；共同暴露开始时间 缺点：只能比较...
We derive several formulae for the sample size required for a study designed using the self-controlled case series method without age effects. We investigate these formulae by simulation, and identify one based on the signed root likelihood ratio statistic which performs well. We extend this metho...
Calculates Sample Size or Power for Matched Case-Control Studies (Stata)Description sampsimcc calculates the power and sample size for a matched case control study. The theory behind this command is described in Dupont (1988) Power Calculations for Matched Case-Control Studies, Biometrics.Mander...
Case-ControlStudies解读 Case-ControlStudies PrinciplesofEpidemiology Lecture10 DonaSchneider,PhD,MPH,FACE Case-ControlStudies Typeofanalyticstudy Unitofobservationandanalysis:Individual(notgroup)PHCO0502PrinciplesofEpidemiology(Schneider)Case-ControlStudies Case-controlstudiesarethemostfrequently...
UNEXP EXP Otherwise, sample is biased, OR is also biased In a cohort study: I0=A0/T0 I1=A1/T1 In a case-control study: Case=A0+A1 Control=K0*T0+K1*T1 If cases are from a population cohort The controls must be selected in such a way that the relative sizes of the denominators ...
12. A retrospective cohort study has shown that there is no significant difference of neonatal birthweight between the PPSD group and the control group (2.9 ± 0.7 kg in PPSD group vs. 3.0 ± 0.4 kg in control group,p = 0.723)2. In addition, a recent systematic review ...