case-cohort studystratified samplingsurvival datatwo-phase designCase-cohort sampling is a commonly used and efficient method for studying large cohorts.In many situations,some covariates are easily measured on all cohort subjects,and surrogate measurements of the expensive covariates also may be observed...
Cohort study: Compare disease rates between exposed individuals non-exposed individuals Higher incidence among exposed points to causes of disease Case-controls study: Compare exposure characteristics between diseased individuals: cases non-diseased individuals: controls ...
Most existing methods of analysis for case–cohort data have concerned the analysis of univariate failure time data. However, clustered failure time data are commonly encountered in public health studies. For example, patients treated at the same center are unlikely to be independent. In this ...
For example, Chen (2001) proposed the generalized case–cohort design and studied its statistical properties under the Cox proportional hazards model (Cox, 1972). Cai and Zeng (2007) compared the hazards function between two samples by the log-rank test and provided the formula for the power ...
The preceding investigation, conducted by our research team, which scrutinized the proclivity of caregivers to vaccinate children with pneumococcal vaccines and their inclination to bear associated costs within a resource-constrained milieu in China, yielded findings indicating that within the study cohort,...
a. A detailed intensive study of a unit, such as a corporation or a corporate division, that stresses factors contributing to its success or failure. b. An exemplary or cautionary model; an instructive example: She is a case study in strong political leadership. American Heritage® Dictionary...
Dalager-Pedersen, M., Søgaard, M., Schønheyder, H. C., Nielsen, H. & Thomsen, R. W. Risk for myocardial infarction and stroke after community-acquired bacteremia: a 20-year population-based cohort study.Circulation129, 1387–1396 (2014). ...
? Case-control Study cases Exposed unexposed a c controls b d odds, That a case was exposed That a control was exosed = a:c = b:d Odds of exposure among cases Odds Ratio = Odds of exposure among controls OR = a/c = ad cb b/d Example: Cohort Study of Body Mass Index (BMI)...
The next generation of systems have the potential to instate an even more radical paradigm shift by, for example, permitting oral delivery of biomacromolecules, allowing for autonomous dose regulation and enabling several doses to be mimicked with a single administration. Their success, however, is...
Exampleofacase-controlstudy:legionnaires’disease（军团病）outbreakin Bogalusa,LA Report:FromOctober10throughNovember131989,33patientswerehospitalizedwithlegionnaires'disease(LD)inBogalusa,LouisianaResearchQuestion:Whatexposurefactorsintheprevious10daysweremorecommonlyfoundamongLDcasescomparedtoLD-freecontrols?•Twenty-...