Targeted DNA demethylation in vivo using dCas9-peptide repeat and scFv-TET1 catalytic domain fusions. Nat. Biotechnol. 34, 1060-1065 (2016).Morita,S., Noguchi,H., Horii,T., Nakabayashi,K., Kimura,M., Okamura,K., Sakai,A., Nakashima,H., Hata,K., Nakashima,K. et al. (2016) ...
The manuscript entitled “Synergistic upregulation of target genes by TET1 and VP64 in the dCas9–SunTag platform” reported synergistic activation of endogenous gene expression via simultaneous tethering of VP64 and TET1 to dCas9–SunTag. The modified system was applied to different loci and desirab...
Synergistic Upregulation of Target Genes by TET1 and VP64 in the dCas9–SunTag Platformdoi:10.3390/IJMS21051574Sumiyo MoritaTakuro HoriiMika KimuraIzuho HatadaInt J Mol Sci