With CAS 7.1.0 RC1 (3e84b9d), server.tomcat.max-http-form-post-size was reduced from Tomcat's default of 2MiB to 40KiB. As a result of this change, SAMLResponses from one of our identity providers ...
"url": "https://www.policia.es/certs/AC_Raiz_DGP-SHA2.cer" }, { "curlOptsList": [ "--tls13-ciphers", "TLS_AES_256_GCM_SHA384" ], "hash": "sha256-ztLM2UJO25WYdY9PW0fMBv0zvKl/kCYadnPBzx753N8=", "url": "https://www.policia.es/certs/AC_Raiz_DGP2-SHA2.cer" } {...
With the aim of discovering potential Cas single effectors, we utilized the pretrained ESM-2 model (esm2_t33_650M_UR50D, https://github.com/facebookresearch/esm27) and fine-tuned it for a multi-class classification task. This task involved classifying Cas9s, Cas12s, Cas13s, and backgroun...
With the aim of discovering potential Cas single effectors, we utilized the pretrained ESM-2 model (esm2_t33_650M_UR50D, https://github.com/facebookresearch/esm27) and fine-tuned it for a multi-class classification task. This task involved classifying Cas9s, Cas12s, Cas13s, and back...
The CRISPR-Cas13 ribonucleases have been widely applied for RNA knockdown and transcriptional modulation owing to their high programmability and specificity. However, the large size of Cas13 effectors and their non-specific RNA cleavage upon target activ
iOdennitciefy, acdlodn1esµLofoifncteelrlelsyt.saAteltthootuhgehcoprerrefsopromnidnigngatwaehlliogfhthsuecPcCesRs pralatete, nanodt amllixwbeyllspgipeentetirnagte. sufficient sequence (threshold 10 reads), to be reported (Table 4). The success of sequencing is highly dependent on the ...
longum M2CF0114 should be classified as B. longum subsp. longum, although the clustering of ANI puts it in the same branch as B. longum subsp. suis. Figure 1. Heatmap based on average nucleotide identity (ANI) of B. longum. The gradation of colour from blue to white to red represents...
For Macintoshes, either Intel or M1/M2: pip install InvokeAI --use-pep517 Configure InvokeAI and install a starting set of image generation models (you only need to do this once): invokeai-configure Launch the web server (do it every time you run InvokeAI): invokeai --web Point ...
and predicted by a machine learning model to be highly active (Metsky et al., in preparation). Moreover, the crRNA was selected for its high predicted specificity toward detection of SARS-CoV-2, versus related viruses, including other bat and mammalian coronaviruses and other human respiratory...