Articular cartilage in the adult is considered a permanent tissue, meaning it has little-to-no turnover throughout adult life. This property differs from cartilage in other locations, such as growth plate carti
Cartilage contains a matrix of collagen, meaning that it does not appear to have large areas of empty space under a microscope. By contrast, blood is composed of cells suspended within plasma. These cells may be far apart or close together based on the concentration of blood observed. Addition...
Articular cartilage in the adult is considered a permanent tissue, meaning it has little-to-no turnover throughout adult life. This property differs from cartilage in other locations, such as growth plate cartilage. ERG expression persists only in the superficial cells of the articular cartilage af...
Cartilage stems from the Latin word ‘’cartilago’’, which has the meaning of ‘’chondros’’ in Greek [27]. Indeed, the first documented realization of cartilage as an indispensable tissue in the human body, has been ascribed to Aristotle in the fourth century BC [28]. Another renowned...
The cartilage in the articular cartilage does not have the ability to regenerate, meaning that damage to the tissue cannot heal [31]. Meanwhile, traditional cartilage repair treatments do not achieve long-term function, rarely restoring the tissue to its original state, resulting in poor treatment...
(DCX), SRY Box transcrip- tion factor 9 (SOX9), and ETS-related gene (ERG) are all genetic markers of cells in the interzone, which is the Maintenance and repair of articular cartilage Articular cartilage in the adult is considered a permanent tissue, meaning it has little-to-no ...
35 The name cricoid is derived from the Greek words krikos and eidos, meaning shaped like a ring, and it is frequently said to have a signet-ring shape. It is thicker and stronger than the thyroid cartilage and represents the only complete cartilaginous ring in the airway. For this reason...
The key to making new cartilage is a good supply of "progenitor" cells. These can develop into cells that make the cushion of cartilage that keeps joints supple. But as we age, the number of progenitor cells falls dramatically, meaning we become less capable of producing new cartilage, says...
57, 58 However, the regenerative potential of the articular cartilage is very limited, meaning that once damaged, cartilage tissue is difficult to repair, propagating a vicious circle.59 How the relatively few numbers of cells maintain daily homeostasis within these unique conditions remains elusive....
Error bars in experimental biology. J Cell Biol 2007;177:7-11. 2. Vaux D. Ten rules for the presentation and interpretation of data in scientific publications. Australian Biochemist 2008;39:37-9. 3. Ranstam J. Sampling uncertainty in medical research. Osteoarthritis Cartilage 2009;17:1416-9...