Blumer MJ , Longato S , Fritsch H ( 2004 ) Cartilage canals in the chicken embryo are involved in the process of endochondral bone formation within the epiphyseal growth plate . Anat Rec 279A , 692 – 700 .Blumer MJ, Longato S, Fritsch H (2004) Cartilage canals in the chicken embryo ...
Also minor amounts of type III, VI, XII and XIV collagens are found in cartilage. Type X collagen is normally restricted in the hypertrophic zone in AC cartilage and growth plate. The three-dimensional network of collagens is filled with PGs that are macromolecules consisting of a central ...
such as the trachea and bronchi. Hyaline cartilage also makes up the fetal model of the future long bones and can be found at the epiphysealgrowth platesof immature bone.Fibrocartilageis found at theacetabulum,intervertebral disks, menisci, and tendinous insertions. It is more pliable thanhyaline...
A radical switch in clonality reveals a stem cell niche in the epiphyseal growth plate Clonal genetic tracing is used to demonstrate that, in mice, longitudinal bone growth during fetal and neonatal periods relies on the gradual consumption of chondroprogenitors, whereas in adults, a stem cell ...
in the IAF fibrillin-positive microfibrils are also seen in an elastin-negative region around cells. In the NP microfibrils are found almost exclusively in the pericellular region, away from elastin fibers in the ECM.51The distribution of microfibrils may reflect differing roles in the OAF, ...
As the cellular component of articular cartilage, chondrocytes are responsible for maintaining in a low-turnover state the unique composition and organization of the matrix that was determined during embryonic and postnatal development. In joint diseases
[4,30]. Vigorous sporting activity during adolescence leads to trauma or shear stress in the growth plate before epiphyseal closure, increasing the epiphyseal extension along the femoral neck [30]. Thus, Cam morphology is not only more prevalent in males, but also higher and greater than that ...
Hypertrophic cartilage is also known as the maturation zone within the epiphyseal plate at the junction between the epiphysis and the diaphysis of growing long bones (Fig. 1). It also occurs as an intermediate tissue during bone fracture repair. 3. Cartilage defects, injuries and degeneration ...
The remaining hyaline cartilage forms the epiphyseal plates that are responsible for long bone growth until the growth plates fuse in late puberty [26]. Using mouse models in which essential components of the UPR signaling pathways have been switched off [[27], [28], [29]], the need for ...
Additionally, upon performing destabilization of the medial meniscus (DMM) surgery on experimental mice, the Osteoarthritis Research Society International (OARSI) scale was found to be higher in Sox9-deleted mutant mice than in control mice. In conclusion, Sox9 is required to keep growth plates open...