Priceman SJ, Forman SJ, Brown CE (2015) Smart CARs engineered for cancer immunotherapy. Curr Opin Oncol 27: 466-474.Priceman SJ, Forman SJ, Brown CE. Smart CARs engineered for cancer immunotherapy. Curr Opin Oncol 2015;27:466-74.Priceman SJ, Forman SJ, Brown CE. Smart CARs engi- nee...
Smart CARs engineered for cancer immunotherapy. Chimeric antigen receptors (CARs) are synthetic immunoreceptors, which can redirect T cells to selectively kill tumor cells, and as 'living drugs' have the potential to generate long-term antitumor immunity. Given their recent clinical s......
1. D. M. Barrett, N. Singh, D. L. Porter, S. A. Grupp, C. H. June, Chimeric antigen receptor therapy for cancer. Annu. Rev. Med. 65, 333–347 (2014). doi:10.1146/annurev-med-060512-150254 Medline 2. B. A. Irving, A. Weiss, The cytoplasmic domain of the T cell ...
相应地,在这些患者中成功的免疫治疗只需要激发这种潜力。 【patients with cancer who derive benefit from T-cell-stimulatory therapy are immunologically primed, before treatment, to mount an anticancer immune response. Correspondingly, succes...
Get shareable link Provided by the Springer Nature SharedIt content-sharing initiative Associated content Human chimeric antigen receptor macrophages for cancer immunotherapy Letter Nature Biotechnology 23 March 2020 Sections Author information Rights and permissions About this article Advertisement...
1. Pearlman, A.H., et al., Targeting public neoantigens for cancer immunotherapy.Nature Cancer, 2021. 2(5): p. 487-497. 2. Leko, V. and S.A. Rosenberg, Identifying and Targeting Human Tumor Antigens for T Cell-Based Imm...
- 《Clinical Cancer Research An Official Journal of the American Association for Cancer Research》 被引量: 62发表: 2014年 Targeting tumor associated macrophages: The new challenge for nanomedicine In addition, the development of TAM-targeted imaging nanostructures, can be used to study the macrophage...
INTRODUCTION: The purpose of this study was to perform a direct comparison of several existing risk-stratification tools for localized prostate cancer in terms of their ability to predict for biochemical failure-free survival (BFFS). Two large databases were used and an external validation of two ...
Mesothelin CAR therapy has the potential to treat multiple solid malignancies. 2015 American Association for Cancer Research. 展开 DOI: 10.1158/2159-8290.CD-15-0583 被引量: 83 年份: 2016 收藏 引用 批量引用 报错 分享 全部来源 免费下载 求助全文 全文购买 国家科技图书文献中心 (权威机构) 万方医学...
摘要: HER2-targeted monoclonal antibodies improve the outcome for advanced breast cancer patients; however, resistance to therapy is still frequent. Epitope masking and steric hindrance ... 查看全部>>关键词: Breast cancer HER2 Trastuzumab Chimeric antigen receptor Immunotherapy Cell therapy Tumor ...