Lutetium-177highspecificactivitynon-carrieraddedpurificationreactorproductionTwo methods of Lu-177 production are reviewed: irradiation of isotopically enriched Lu- 176 (direct way) and irradiation of ytterbium enriched with Yb-176 (indirect way). Based on neutronphysical calculations Lu-177 yield and ...
To satisfy this criterion, an alternative nuclear production route, the 176Yb(n, ) 177Yb (T1/2=1.911h) → 177Lu process was examined using commercially available enriched 176Yb (97.6 0.1%) oxide (176Yb2O3) to produce no carrier added 177Lu.The most difficult step in the production of ...
Production of No-Carrier Added Lutetium-177 by Irradiation of Enriched Ytterbium-176 Two methods of Lu-177 production are reviewed: irradiation of isotopically enriched Lu- 176 (direct way) and irradiation of ytterbium enriched with Yb-176 ... V A. Tarasov,O I. Andreev,E G. Romanov,... ...
Conclusion: The studies carried out suggest that therapeutic doses of [177Lu]PSMA-11 could be prepared by using low specific activity, carrier added 177Lu. Clinical studies demonstrated the uptake and retention of the tracer in prostate cancer lesions. 展开 ...
Besides, PIO noticeably weakened the inhibition of the mPTP opening by added ADP (Figure 2B) and ATP (Figure 2C) (ADP and ATP are strong natural mPTP inhibitors, which can be present in the cytosol of living cells at millimolar concentrations). Thus, PIO does not induce the mPTP opening ...
2008. Quality control of no-carrier-added 90YCl3 by estimating the labeling efficiency using its reaction with DOTATOC. J Radioanal Nucl Chem 278:25-29.Eigner Henke, K., Beran, M., Sˇrank, J., Melichar, F., 2008. Quality control of no- carrier-added 90YCl3 by estimating the ...
The shipowners had to pay damages as, regardless of the excepted peril, they had breached their duty to take reasonable care (emphasis added) for the goods entrusted to them. 44. A fundamental breach is one that goes to the roots of the contract, and it usually occurs when either party ...
0.02 mL COX-2 solution was added to start the reaction. The increase in absorbance during the room temperature incubation was measured at 590 nm. Positive (assay kit COX-2 inhibitor DuP-697) and negative (blank) samples (buffer instead of examined sample) were run at the same time. The ...
www.nature.com/scientificreports OPEN Solute carrier 41A3 encodes for a mitochondrial Mg2+ efflux system received: 30 January 2016 accepted: 24 May 2016 Published: 15 June 2016 Lucia Mastrototaro1, Alina Smorodchenko2, Jörg R. Aschenbach1, Martin Kolisek1 & Gerhard Sponder1 ...
3 Other studies have shown an unusually high prevalence of thalassemia among people in the southern prov- inces of China such as Guangxi, Guangdong, and Hainan.4–6 Our recent investigations added the Yunnan province to the high-prevalence regions of thalassemia.7 Most individuals carry four α-...