DMF or DMSO, from the corresponding 2-cyano-methylimidazoles (VIII), which are known compounds, and the appropriate phenylethylhalides of formula (IX), which are known compounds or can be easily prepared by known methods. ##STR11## wherein Hal means halogen, e.g. chlorine or bromine, and...
The compound of formula (V) wherein E is (C6 H5)3 P-(+) may be prepared by reacting a compound of formula (VIII) ##STR41## wherein Z2, n1, R3, R4, X, n2, R6 are as defined above and Hal is a halogen atom, with 1-1.2 molar equivalent of triphenylphosphine in an inert ...
Stabat Mater in F-Minor for Soprano and Strings, G. 532 (1781 version): VIII. Virgo Virginum - Andantino Il Quartettone、 Tatiana Korovina、 Carlo De Martini 试听 5:25 9 Stabat Mater in F-Minor for Soprano and Strings, G. 532 (1781 version): IX. Fac Ut Portem - Larghetto Il...
A compound of formula (V) in which A is a halogen atom may be obtained by halogenating the corresponding compound of formula (VIII) ##STR33## wherein R1, R2, R3, R4, R5, R6 and Z are as defined above. The halogenation of a compound of formula (VIII) to give a compound of form...
vacuum. The resulting red solution was adjusted to pH 3.5 with anhydrous methanolic hydrogen chloride, an excess of ethyl ether was added to give 4'-C-methyl-4'-O-methyl-adriamycin (VIII, 0.21 g) as the hydrochloride: m.p. 185°-186° (dec.); [α]D23° =+291° (c=0.05, in ...
To a solution of 0.065 g of racemic 4-demethoxy-6-deoxydaunomycinone (II: R1=OH, R2=H), prepared as described in Example VIII, in 45 ml of anhydrous dichloromethane, there were added 1 g of molecular sieve (4 Å Merck), 0.079 g of 2,3,6-trideoxy-3-trifluoroacetamido-4-O-tr...