VRAYLAR capsules are intended for oral administration only. Each hard gelatin capsule contains a white to off-white powder of cariprazine HCl, which is equivalent to 1.5, 3, 4.5, or 6 mg of cariprazine base. In addition, capsules include the following inactive ingredients: gelatin, magnesium ste...
1.5 mg orally once initially; may increase to 3 mg/day on day 2 Depending upon clinical response and tolerability, further dose adjustments can be made in 1.5 to 3-mg increments; dosing range is 1.5-6 mg orally once daily Dosages above 6 mg/day do not confer increased effectiveness suffic...
Introduction: Several studies have demonstrated the unfavorable and neurotoxic effects of untreated psychosis (UP) on the brain. An estimated 10 to 12 cc of brain tissue could be potentially damaged due to neuroinflammation and oxidative stress when a first episode of psy...
and adjust the dosage according to the individual situation and condition. In general, the dose should be started at a low dose and gradually increased to avoid the occurrence of side effects. Common side effects include
Discontinuation causes were inefficacy (5/18); clinical worsening (10/18); side effects (3/18); hypomanic shift (2/18). Conclusions: Despite the relatively small population examined and the observational design, our results suggest that cariprazine may represent an effec...