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More questions arise when thinking of the cargo-selective specificity of (1) alternative macroautophagy in developing and stressed cells in general or (2) autophagy adaptors in particular, which may or not be driven by PTM modulations. More specifically, it still remains to be elucidated (1) wh...
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Proc. Natl Acad. Sci. USA 97, 9482–9486 (2000). CAS PubMed PubMed Central Google Scholar Yildiz, A. et al. Myosin V walks hand-over-hand: single fluorophore imaging with 1.5-nm localization. Science 300, 2061–2065 (2003). Describes the use of super-resolution light microscopy to ...
Fig. 2: PGRMC1 binds to mutant POMC and promotes its RTN3-dependent ER-phagic clearance. Full size image PGRMC1 uses its luminal domain to recruit cargo Fig. 3: PGRMC1 uses its luminal domain to recruit cargo. Full size image