The overall annual mortality from sudden death is 3-5% in adults and at least 6% in children and young adults. However, severity of disease and prognosis varies widely according to the genetic features involved. Certain genes are associated with a worse prognosis. Restrictive cardiomyopathy The wor...
Furthermore, since respiratory muscle is also skeletal muscle, it is possible that the effects here also add to the clinical disorder.35There is a strong relationship between skeletal muscle phenotype and maximal peak O2consumption in healthy individuals, and the prognosis in CHF has been shown to...
Hypertrophic cardiomyopathy (HCM) is a genetic heart disease that is associated with many pathological features, such as a reduction in global longitudinal strain (GLS), myofiber disarray and hypertrophy. The effects of these features on left ventricle (
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As for most of the acquired causes, a genetic susceptibility—mainly TTNtv—might facilitate the development of a peripartum dilated cardiomyopathy29and indicate worse prognosis. Therefore, genetic counselling and testing is recommended, and treatment should be adapted accordingly. 64 对于大多数获得性原...
Outcomes and phenotypic expression of rare variants in hypertrophic cardiomyopathy genes in over 200,000 adultsEpidemiology, Prognosis, OutcomeBACKGROUND. Hypertrophic cardiomyopathy (HCM) is caused by rare variants in sarcomere-encoding genes, but little is known about the clinical significance of these ...
Cheng S, Fang M, Cui C et al (2018) LGE-CMR-derived texture features reflect poor prognosis in hypertrophic cardiomyopathy patients with systolic dysfunction: preliminary results. Eur Radiol 28:4615–4624 Article PubMed Google Scholar Galati G, Leone O, Pasquale F et al (2016) Histological ...
Liu JE, Palmieri V, Roman MJ, et al. Cardiovascular disease and prognosis in adults with glucose disorders: the Strong Heart Study. J Am Coll Cardiol. 2000;35:263A. ArticleGoogle Scholar Verdecchia P, Schillaci G, Borgioni C, Ciucci A, Gattobigio R, Zampi I, Porcellati C. Prognostic...
Prevalence and prognosis of atenolol-responsive systolic anterior motion of the septal mitral valve leaflet in young cats with severe dynamic left ventricular outflow tract obstruction. Animals 12(24), 3509. https://doi.org/10.3390/ani12243509 (2022). Article PubMed PubMed Central Google Scholar ...
Effect of stromal-cell-derived factor 1 on stem-cell homing and tissue regeneration in ischaemic cardiomyopathy Long-term follow-up of 34 adults with isolated left ventricular noncompaction: a distinct cardiomyopathy with poor prognosis